1YXX
Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
Summary for 1YXX
Entry DOI | 10.2210/pdb1yxx/pdb |
Related | 1YWV 1YXS 1YXT 1YXU 1YXV |
Descriptor | Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, ... (4 entities in total) |
Functional Keywords | ser/thr protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 34139.65 |
Authors | Kumar, A.,Mandiyan, V.,Suzuki, Y.,Zhang, C.,Rice, J.,Tsai, J.,Artis, D.R.,Ibrahim, P.,Bremer, R. (deposition date: 2005-02-22, release date: 2005-04-26, Last modification date: 2024-02-14) |
Primary citation | Kumar, A.,Mandiyan, V.,Suzuki, Y.,Zhang, C.,Rice, J.,Tsai, J.,Artis, D.R.,Ibrahim, P.,Bremer, R. Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma. J.Mol.Biol., 348:183-193, 2005 Cited by PubMed: 15808862DOI: 10.1016/j.jmb.2005.02.039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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