1S1J
Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1
Summary for 1S1J
Entry DOI | 10.2210/pdb1s1j/pdb |
Descriptor | Cell division protein zipA, (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one (3 entities in total) |
Functional Keywords | cell cycle |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane; Single-pass type I membrane protein: P77173 |
Total number of polymer chains | 2 |
Total formula weight | 32509.27 |
Authors | Jenning, L.D.,Foreman, K.W.,Rush III, T.S.,Tsao, D.H.,Mosyak, L.,Li, Y.,Sukhdeo, M.N.,Ding, W.,Dushin, E.G.,Kenney, C.H.,Moghazeh, S.L.,Peterson, P.J.,Ruzin, A.V.,Tuckman, M.,Sutherland, A.G. (deposition date: 2004-01-06, release date: 2004-05-04, Last modification date: 2024-02-14) |
Primary citation | Jennings, L.D.,Foreman, K.W.,Rush III, T.S.,Tsao, D.H.,Mosyak, L.,Li, Y.,Sukhdeo, M.N.,Ding, W.,Dushin, E.G.,Kenny, C.H.,Moghazeh, S.L.,Petersen, P.J.,Ruzin, A.V.,Tuckman, M.,Sutherland, A.G. Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction Bioorg.Med.Chem.Lett., 14:1427-1431, 2004 Cited by PubMed: 15006376DOI: 10.1016/j.bmcl.2004.01.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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