1PY4
Beta2 microglobulin mutant H31Y displays hints for amyloid formations
Summary for 1PY4
Entry DOI | 10.2210/pdb1py4/pdb |
Descriptor | Beta-2-microglobulin precursor (2 entities in total) |
Functional Keywords | amyloid, dialysis related amyloidosis, c-type immunoglobulin, protein mutant, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P61769 |
Total number of polymer chains | 4 |
Total formula weight | 47617.53 |
Authors | Rosano, C.,Zuccotti, S.,Mangione, P.,Giorgetti, S.,Bellotti, V.,Pettirossi, F.,Corazza, A.,Viglino, P.,Esposito, G.,Bolognesi, M. (deposition date: 2003-07-08, release date: 2004-05-04, Last modification date: 2023-08-16) |
Primary citation | Rosano, C.,Zuccotti, S.,Mangione, P.,Giorgetti, S.,Bellotti, V.,Pettirossi, F.,Corazza, A.,Viglino, P.,Esposito, G.,Bolognesi, M. beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation J.Mol.Biol., 335:1051-1064, 2004 Cited by PubMed: 14698299DOI: 10.1016/j.jmb.2003.11.040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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