1P6K
Rat neuronal NOS D597N mutant heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound
Summary for 1P6K
Entry DOI | 10.2210/pdb1p6k/pdb |
Related | 1P6H 1P6I 1P6J 1P6L 1P6M 1P6N |
Descriptor | Nitric-oxide synthase, brain, D-MANNITOL, ACETATE ION, ... (8 entities in total) |
Functional Keywords | nitric oxide synthase, oxidoreductase, heme-enzyme |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cell membrane, sarcolemma; Peripheral membrane protein (By similarity): P29476 |
Total number of polymer chains | 2 |
Total formula weight | 100408.96 |
Authors | Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.-M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. (deposition date: 2003-04-29, release date: 2004-01-13, Last modification date: 2024-02-14) |
Primary citation | Flinspach, M.L.,Li, H.,Jamal, J.,Yang, W.,Huang, H.,Hah, J.M.,Gomez-Vidal, J.A.,Litzinger, E.A.,Silverman, R.B.,Poulos, T.L. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11:54-59, 2004 Cited by PubMed: 14718923DOI: 10.1038/nsmb704 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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