1P2A
The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor
Summary for 1P2A
Entry DOI | 10.2210/pdb1p2a/pdb |
Related | 1FVT |
Descriptor | Cell division protein kinase 2, 5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE (3 entities in total) |
Functional Keywords | cyclin dependent kinase, naphthostyril oxindole, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34286.81 |
Authors | Liu, J.-J.,Dermatakis, A.,Lukacs, C.M.,Konzelmann, F.,Chen, Y.,Kammlott, U.,Depinto, W.,Yang, H.,Yin, X.,Chen, Y.,Schutt, A.,Simcox, M.E.,Luk, K.-C. (deposition date: 2003-04-15, release date: 2003-07-15, Last modification date: 2024-02-14) |
Primary citation | Liu, J.-J.,Dermatakis, A.,Lukacs, C.M.,Konzelmann, F.,Chen, Y.,Kammlott, U.,Depinto, W.,Yang, H.,Yin, X.,Chen, Y.,Schutt, A.,Simcox, M.E.,Luk, K.-C. 3,5,6-Trisubstituted Naphthostyrils as CDK2 Inhibitors BIOORG.MED.CHEM., 13:2465-2468, 2003 Cited by PubMed: 12852944DOI: 10.1016/S0960-894X(03)00488-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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