1N2R
A natural selected dimorphism in HLA B*44 alters self, peptide reportoire and T cell recognition.
Summary for 1N2R
Entry DOI | 10.2210/pdb1n2r/pdb |
Related | 1M6O |
Descriptor | HLA class I histocompatibility antigen, BW-44(B-12) B*4403 alpha chain, Beta-2-microglobulin, HLA DPA*0201 PEPTIDE, ... (5 entities in total) |
Functional Keywords | mhc i, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30481 Secreted: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44936.76 |
Authors | Macdonald, W.A.,Purcell, A.W.,Williams, D.S.,Mifsud, N.,Ely, L.K.,Gorman, J.J.,Clements, C.S.,Kjer-Nielsen, L.,Koelle, D.M.,Brooks, A.G.,Lovrecz, G.O.,Lu, L.,Rossjohn, J.,McCluskey, J. (deposition date: 2002-10-24, release date: 2004-03-16, Last modification date: 2011-07-13) |
Primary citation | Macdonald, W.A.,Purcell, A.W.,Mifsud, N.A.,Ely, L.K.,Williams, D.S.,Chang, L.,Gorman, J.J.,Clements, C.S.,Kjer-Nielsen, L.,Koelle, D.M.,Burrows, S.R.,Tait, B.D.,Holdsworth, R.,Brooks, A.G.,Lovrecz, G.O.,Lu, L.,Rossjohn, J.,McCluskey, J. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J.Exp.Med., 198:679-691, 2003 Cited by PubMed: 12939341DOI: 10.1084/jem.20030066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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