1JQ8
Design of specific inhibitors of phospholipase A2: Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.0 resolution
Summary for 1JQ8
Entry DOI | 10.2210/pdb1jq8/pdb |
Related | 1CL5 1FB2 1FE7 1FV0 1JQ9 |
Descriptor | Phospholipase A2, Peptide inhibitor, SULFATE ION, ... (5 entities in total) |
Functional Keywords | neurotoxic, designed peptide, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Daboia russellii pulchella More |
Total number of polymer chains | 3 |
Total formula weight | 28101.41 |
Authors | Chandra, V.,Jasti, J.,Kaur, P.,Dey, S.,Betzel, C.,Singh, T.P. (deposition date: 2001-08-04, release date: 2002-11-06, Last modification date: 2023-10-25) |
Primary citation | Chandra, V.,Jasti, J.,Kaur, P.,Dey, S.,Srinivasan, A.,Betzel, C.h.,Singh, T.P. Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS). ACTA CRYSTALLOGR.,SECT.D, 58:1813-1819, 2002 Cited by PubMed: 12351825DOI: 10.1107/S0907444902013720 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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