1GYP

CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE

Summary for 1GYP

Entry DOI	10.2210/pdb1gyp/pdb
Descriptor	GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	oxidoreductase (aldehyde(d)-nad+(a))
Biological source	Leishmania mexicana
Cellular location	Glycosome: Q27890
Total number of polymer chains	4
Total formula weight	158185.98
Authors	Kim, H.,Feil, I.K.,Verlinde, C.L.M.J.,Petra, P.H.,Hol, W.G.J. (deposition date: 1995-08-01, release date: 1995-12-07, Last modification date: 2024-02-07)
Primary citation	Kim, H.,Feil, I.K.,Verlinde, C.L.,Petra, P.H.,Hol, W.G. Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site. Biochemistry, 34:14975-14986, 1995 Cited by PubMed: 7578111 DOI: 10.1021/bi00046a004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation