1FZZ

THE CRYSTAL STRUCTURE OF THE COMPLEX OF NON-PEPTIDIC INHIBITOR ONO-6818 AND PORCINE PANCREATIC ELASTASE.

Summary for 1FZZ

Entry DOI	10.2210/pdb1fzz/pdb
Descriptor	ELASTASE 1, 2-(5-AMINO-6-OXO-2-PHENYL-6H-PYRIMIDIN-1-YL)-N-[2-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-1-(METHYLETHYL)-2-HYDROXYETHYL]ACETAMIDE (3 entities in total)
Functional Keywords	enzyme-inhibitor complex, hydrolase
Biological source	Sus scrofa (pig)
Cellular location	Secreted: P00772
Total number of polymer chains	1
Total formula weight	26383.54
Authors	Odagaki, Y.,Ohmoto, K.,Matsuoka, S.,Hamanaka, N.,Nakai, H.,Toda, M.,Katsuya, Y. (deposition date: 2000-10-04, release date: 2001-10-04, Last modification date: 2017-10-04)
Primary citation	Odagaki, Y.,Ohmoto, K.,Matsuoka, S.,Hamanaka, N.,Nakai, H.,Toda, M.,Katsuya, Y. The crystal structure of the complex of non-peptidic inhibitor of human neutrophil elastase ONO-6818 and porcine pancreatic elastase. Bioorg.Med.Chem., 9:647-651, 2001 Cited by PubMed: 11310599 DOI: 10.1016/S0968-0896(00)00277-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation