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1D5Z

X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB

Summary for 1D5Z
Entry DOI10.2210/pdb1d5z/pdb
Related1D5M 1D5X 1D6E
Related PRD IDPRD_000456
DescriptorPROTEIN (HLA CLASS II HISTOCOMPATIBILITY ANTIGEN), PROTEIN (ENTEROTOXIN TYPE B), PROTEIN (PEPTIDOMIMETIC INHIBITOR), ... (5 entities in total)
Functional Keywordsmhc class ii-superantigen complex, immune system-peptide inhibitor complex, peptidomimetic inhibitor, immune system/peptide inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Single-pass type I membrane protein: P01903 P13760
Secreted: P01552
Total number of polymer chains4
Total formula weight72862.93
Authors
Swain, A.,Crowther, R.,Kammlott, U. (deposition date: 1999-10-12, release date: 2000-06-28, Last modification date: 2023-11-15)
Primary citationBolin, D.R.,Swain, A.L.,Sarabu, R.,Berthel, S.J.,Gillespie, P.,Huby, N.J.,Makofske, R.,Orzechowski, L.,Perrotta, A.,Toth, K.,Cooper, J.P.,Jiang, N.,Falcioni, F.,Campbell, R.,Cox, D.,Gaizband, D.,Belunis, C.J.,Vidovic, D.,Ito, K.,Crowther, R.,Kammlott, U.,Zhang, X.,Palermo, R.,Weber, D.,Guenot, J.,Nagy, Z.,Olson, G.L.
Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43:2135-2148, 2000
Cited by
PubMed: 10841792
DOI: 10.1021/jm000034h
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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数据于2024-03-13公开中

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