1A71
TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL
Summary for 1A71
Entry DOI | 10.2210/pdb1a71/pdb |
Descriptor | LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | oxidoreductase (nad(a)-choh(d)), liver, alcohol, dehydrogenase, ladh, active site mutant, oxidoreductase |
Biological source | Equus caballus (horse) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 2 |
Total formula weight | 81517.08 |
Authors | Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M. (deposition date: 1998-03-19, release date: 1998-06-17, Last modification date: 2024-05-22) |
Primary citation | Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M. Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes. Biochemistry, 37:9295-9304, 1998 Cited by PubMed: 9649310DOI: 10.1021/bi973184b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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