186D

SOLUTION STRUCTURE OF THE TETRAHYMENA TELOMERIC REPEAT D(T2G4)4 G-TETRAPLEX

186D の概要

• エントリーDOI: 10.2210/pdb186d/pdb
• 分子名称: DNA (5'-D(*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3') (1 entity in total)
• 機能のキーワード: dna
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 7655.88

構造登録者

Wang, Y.,Patel, D.J. (登録日: 1994-08-22, 公開日: 1994-11-01, 最終更新日: 2024-05-22)

主引用文献

Wang, Y.,Patel, D.J.
Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex.
Structure, 2:1141-1156, 1994

PubMed Abstract: Telomeres in eukaryotic organisms are protein-DNA complexes which are essential for the protection and replication of chromosomal termini. The telomeric DNA of Tetrahymena consists of T2G4 repeats, and models have been previously proposed for the intramolecular folded structure of the d(T2G4)4 sequence based on chemical footprinting and cross-linking data. A high-resolution solution structure of this sequence would allow comparison with the structures of related G-tetraplexes.

PubMed: 7704525
DOI: 10.1016/S0969-2126(94)00117-0

実験手法

SOLUTION NMR