166D
DRUG-DNA MINOR GROOVE RECOGNITION: CRYSTAL STRUCTURE OF GAMMA-OXAPENTAMIDINE COMPLEXED WITH D(CGCGAATTCGCG)2
Summary for 166D
Entry DOI | 10.2210/pdb166d/pdb |
Descriptor | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 1,5-DI(4-AMIDINOPHENOXY)-3-OXA-PENTANE (3 entities in total) |
Functional Keywords | b-dna, double helix, complexed with drug, dna |
Total number of polymer chains | 2 |
Total formula weight | 7669.18 |
Authors | Nunn, C.M.,Jenkins, T.C.,Neidle, S. (deposition date: 1994-03-17, release date: 1994-10-15, Last modification date: 2024-02-07) |
Primary citation | Nunn, C.M.,Jenkins, T.C.,Neidle, S. Crystal structure of gamma-oxapentamidine complexed with d(CGCGAATTCGCG)2. The effects of drug structural change on DNA minor-groove recognition. Eur.J.Biochem., 226:953-961, 1994 Cited by PubMed: 7813486DOI: 10.1111/j.1432-1033.1994.00953.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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