149D

SOLUTION STRUCTURE OF A PYRIMIDINE(DOT)PURINE(DOT) PYRIMIDINE DNA TRIPLEX CONTAINING T(DOT)AT, C+(DOT)GC AND G(DOT)TA TRIPLES

149D の概要

• エントリーDOI: 10.2210/pdb149d/pdb
• 分子名称: 5'-D(*CP*CP*TP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*AP*GP*G)-3', 5'-D(*CP*TP*TP*GP*TP*CP*C)-3' (3 entities in total)
• 機能のキーワード: dna, triplex
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 6299.22

構造登録者

Radhakrishnan, I.,Patel, D.J. (登録日: 1993-11-15, 公開日: 1994-04-30, 最終更新日: 2024-05-22)

主引用文献

Radhakrishnan, I.,Patel, D.J.
Solution structure of a pyrimidine.purine.pyrimidine DNA triplex containing T.AT, C+.GC and G.TA triples.
Structure, 2:17-, 1994

PubMed Abstract: Under certain conditions, homopyrimidine oligonucleotides can bind to complementary homopurine sequences in homopurine-homopyrimidine segments of duplex DNA to form triple helical structures. Besides having biological implications in vivo, this property has been exploited in molecular biology applications. This approach is limited by a lack of knowledge about the recognition by the third strand of pyrimidine residues in Watson-Crick base pairs.

PubMed: 8075980
DOI: 10.1016/S0969-2126(00)00005-8

実験手法

SOLUTION NMR