6QPL

Crystal structure of Spindlin1 in complex with the inhibitor MS31

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
BSpindlin-1polymer22225499.81
UniProt (Q9Y657)
Pfam (PF02513)
Homo sapiens (Human)Ovarian cancer-related protein,Spindlin1
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.22
DIMETHYL SULFOXIDEnon-polymer78.12
[3-(aminomethyl)-5-[3-(1,3-dihydroisoindol-2-yl)propoxy]-4-methoxy-phenyl]methanaminenon-polymer341.41
GLYCINEnon-polymer75.11
PHOSPHATE IONnon-polymer95.01
GLYCEROLnon-polymer92.11
waterwater18.0108

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight25499.8
Non-Polymers*Number of molecules8
Total molecular weight996.2
All*Total molecular weight26496.0
*Water molecules are not included.