6QIB
The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase epsilon catalytic subunit A | polymer | 1192 | 137202.7 | 1 | UniProt (P21951) Pfam (PF03104) Pfam (PF22634) In PDB | Saccharomyces cerevisiae (Baker's yeast) | DNA polymerase II subunit A |
2 | P | Primer_11ddC | polymer | 11 | 3293.2 | 1 | synthetic construct | ||
3 | T | Template16 | polymer | 16 | 4889.2 | 1 | synthetic construct | ||
4 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
5 | A | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
6 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: 1 - 1187 (UniProt: P21951)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Gly -3 | - | expression tag |
Asp -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Ala 290 | Asp 290 | engineered mutation |
Ala 292 | Glu 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 145385.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 882.9 | |
All* | Total formula weight | 146268.0 |