5BMV

CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX

エンティティ

Entity ID	鎖名	説明	種類	鎖長	化学式量	分子数	データベース名(アクセス番号)	由来する生物種	エンティティの一般名
1	A, C	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB	Bos taurus (Bovine)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B, D	Tubulin beta chain	polymer	445	49907.8	2	UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB	Sus scrofa (Pig)	Beta-tubulin
3	E	Stathmin-4	polymer	143	16844.2	1	UniProt (P63043) Pfam (PF00836) In PDB	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F	Uncharacterized protein	polymer	384	44378.5	1	UniProt (E1BQ43) In PDB	Gallus gallus (Chicken)	Tubulin-tyrosine ligase
5	A, C	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	D, A, B, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
7	A, B, C	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
8	A, B, C	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
9	B, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
10	B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
11	C	(2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE	non-polymer		811.0	1	Chemie (VLB)
12	F	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
13		water	water		18.0	219	Chemie (HOH)

配列変更

E: 5 - 145 (UniProt: P63043)

PDB	外部データベース	詳細
Met 3	-	expression tag
Ala 4	-	expression tag

F: 1 - 378 (UniProt: E1BQ43)

PDB	外部データベース	詳細
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

非対称単位の内容

タンパク質・ 核酸鎖	鎖の数	6
	化学式量合計	261447.1
タンパク質・ 核酸・ 糖鎖以外*	分子数	22
	化学式量合計	4501.5
全て*	化学式量合計	265948.6

*水分子は含んでいません