3ZCW

Eg5 - New allosteric binding site

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
AKINESIN-LIKE PROTEIN KIF11polymer34838807.11
UniProt (P52732)
Pfam (PF00225)
HOMO SAPIENS (HUMAN)@PDBjKINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HKSP, KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21
MAGNESIUM IONnon-polymer24.31
(2E)-2-(3-fluoranyl-4-methoxy-phenyl)imino-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-benzimidazole-5-carboxylic acidnon-polymer459.42
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31
DI(HYDROXYETHYL)ETHERnon-polymer106.11
waterwater18.0450

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight38807.1
Non-Polymers*Number of molecules6
Total molecular weight1714.7
All*Total molecular weight40521.8
*Water molecules are not included.