3JZI

Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series

エンティティ

Entity ID	鎖名	説明	種類	鎖長	化学式量	分子数	データベース名(アクセス番号)	由来する生物種	エンティティの一般名
1	A, B	Biotin carboxylase	polymer	486	53507.1	2	UniProt (P24182) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) In PDB	Escherichia coli	Acetyl-CoA carboxylase subunit A, ACC
2	A, B	7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide	non-polymer		442.0	2	Chemie (JZL)
3		water	water		18.0	400	Chemie (HOH)

配列変更

A, B: 1 - 449 (UniProt: P24182)

PDB	外部データベース	詳細
Met -20	-	expression tag
Gly -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag
Ser 450	-	expression tag
Asp 451	-	expression tag
Pro 452	-	expression tag
Asn 453	-	expression tag
Ser 454	-	expression tag
Ser 455	-	expression tag
Ser 456	-	expression tag
Val 457	-	expression tag
Asp 458	-	expression tag
Lys 459	-	expression tag
Leu 460	-	expression tag
Ala 461	-	expression tag
Ala 462	-	expression tag
Ala 463	-	expression tag
Leu 464	-	expression tag
Glu 465	-	expression tag

非対称単位の内容

タンパク質・ 核酸鎖	鎖の数	2
	化学式量合計	107014.1
タンパク質・ 核酸・ 糖鎖以外*	分子数	2
	化学式量合計	883.9
全て*	化学式量合計	107898.0

*水分子は含んでいません