3DZG
Crystal structure of human CD38 extracellular domain, ara-F-ribose-5'-phosphate/nicotinamide complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | ADP-ribosyl cyclase 1 | polymer | 262 | 30380.4 | 2 | UniProt (P28907) Pfam (PF02267) In PDB | Homo sapiens | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38 antigen |
2 | A, B | 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose | non-polymer | 232.1 | 2 | Chemie (RF5) | |||
3 | A, B | NICOTINAMIDE | non-polymer | 122.1 | 2 | Chemie (NCA) | |||
4 | water | water | 18.0 | 468 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 300 (UniProt: P28907)
PDB | External Database | Details |
---|---|---|
Lys 39 | - | expression tag |
Arg 40 | - | expression tag |
Glu 41 | - | expression tag |
Ala 42 | - | expression tag |
Glu 43 | - | expression tag |
Ala 44 | - | expression tag |
Thr 49 | Gln 49 | engineered mutation |
Asp 100 | Asn 100 | engineered mutation |
Asp 164 | Asn 164 | engineered mutation |
Asp 209 | Asn 209 | engineered mutation |
Asp 219 | Asn 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60760.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 708.5 | |
All* | Total formula weight | 61469.2 |