2O1Y
Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand
エンティティ
| Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
| 1 | A | Apoptosis regulator Bcl-X | polymer | 181 | 20804.9 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl-2-like 1 protein |
| 2 | A | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | non-polymer | 694.8 | 1 | Chemie (43B) |
配列変更
A: 5 - 48 (UniProt: Q07817)
A: 89 - 213 (UniProt: Q07817)
| PDB | 外部データベース | 詳細 |
|---|---|---|
| Met 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Met 3 | - | cloning artifact |
| Ala 4 | - | cloning artifact |
| Leu 214 | - | cloning artifact |
| Glu 215 | - | cloning artifact |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
配列ビューア
非対称単位の内容
| タンパク質・ 核酸鎖 | 鎖の数 | 1 |
| 化学式量合計 | 20804.9 | |
| タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 1 |
| 化学式量合計 | 694.8 | |
| 全て* | 化学式量合計 | 21499.8 |
