2GQ2
Mycobacterium tuberculosis ThyX-NADP complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Thymidylate synthase thyX | polymer | 258 | 28970.0 | 4 | UniProt (P66930) Pfam (PF02511) UniProt (by SIFTS) (P9WG57) In PDB | Mycobacterium tuberculosis H37Rv | TS, TSase |
2 | D, A, B, C | IODIDE ION | non-polymer | 126.9 | 15 | Chemie (IOD) | |||
3 | D, A, B, C | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
4 | D, A, B, C | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
5 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
6 | D, A, B, C | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
7 | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 250 (UniProt: P66930)
PDB | External Database | Details |
---|---|---|
Mse 1 | Met 1 | modified residue |
Mse 65 | Ile 65 | engineered mutation |
Mse 122 | Met 122 | modified residue |
Mse 175 | Leu 175 | engineered mutation |
Mse 198 | Met 198 | modified residue |
Leu 251 | - | cloning artifact |
Glu 252 | - | cloning artifact |
His 253 | - | expression tag |
His 254 | - | expression tag |
His 255 | - | expression tag |
His 256 | - | expression tag |
His 257 | - | expression tag |
His 258 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 115879.9 | |
Non-Polymers* | Number of molecules | 31 |
Total formula weight | 5828.4 | |
All* | Total formula weight | 121708.3 |