2F4V

30S ribosome + designer antibiotic

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	16S ribosomal RNA	polymer	1511	490595.4	1	GenBank (155076)	Thermus thermophilus
2	Z	5'-R(P*UP*UP*CP*U)-3'	polymer	4	1178.7	1		Thermus thermophilus
3	B	30S ribosomal protein S2	polymer	256	29317.7	1	UniProt (P80371) Pfam (PF00318) In PDB	Thermus thermophilus
4	C	30S ribosomal protein S3	polymer	239	26751.1	1	UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB	Thermus thermophilus
5	D	30S ribosomal protein S4	polymer	209	24373.4	1	UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB	Thermus thermophilus
6	E	30S ribosomal protein S5	polymer	162	17583.4	1	UniProt (P27152) Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (Q5SHQ5) In PDB	Thermus thermophilus
7	F	30S ribosomal protein S6	polymer	101	11988.8	1	UniProt (P23370) Pfam (PF01250) UniProt (by SIFTS) (Q5SLP8) In PDB	Thermus thermophilus	TS9
8	G	30S ribosomal protein S7	polymer	156	18051.0	1	UniProt (P17291) Pfam (PF00177) In PDB	Thermus thermophilus
9	H	30S ribosomal protein S8	polymer	138	15868.6	1	UniProt (P24319) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9) In PDB	Thermus thermophilus
10	I	30S ribosomal protein S9	polymer	128	14429.7	1	UniProt (P62669) Pfam (PF00380) UniProt (by SIFTS) (P80374) In PDB	Thermus thermophilus
11	J	30S ribosomal protein S10	polymer	105	11955.0	1	UniProt (P80375) Pfam (PF00338) UniProt (by SIFTS) (Q5SHN7) In PDB	Thermus thermophilus
12	K	30S ribosomal protein S11	polymer	129	13737.9	1	UniProt (P80376) Pfam (PF00411) In PDB	Thermus thermophilus
13	L	30S ribosomal protein S12	polymer	132	14637.4	1	UniProt (P17293) Pfam (PF00164) UniProt (by SIFTS) (Q5SHN3) In PDB	Thermus thermophilus
14	M	30S ribosomal protein S13	polymer	126	14338.9	1	UniProt (P80377) Pfam (PF00416) In PDB	Thermus thermophilus
15	N	30S ribosomal protein S14	polymer	61	7158.7	1	UniProt (P24320) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6) In PDB	Thermus thermophilus
16	O	30S ribosomal protein S15	polymer	89	10578.4	1	UniProt (P80378) Pfam (PF00312) UniProt (by SIFTS) (Q5SJ76) In PDB	Thermus thermophilus
17	P	30S ribosomal protein S16	polymer	88	10410.0	1	UniProt (Q5SJH3) Pfam (PF00886) In PDB	Thermus thermophilus
18	Q	30S ribosomal protein S17	polymer	105	12324.7	1	UniProt (P24321) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7) In PDB	Thermus thermophilus
19	R	30S ribosomal protein S18	polymer	88	10244.3	1	UniProt (P80382) Pfam (PF01084) UniProt (by SIFTS) (Q5SLQ0) In PDB	Thermus thermophilus
20	S	30S ribosomal protein S19	polymer	93	10605.5	1	UniProt (P80381) Pfam (PF00203) UniProt (by SIFTS) (Q5SHP2) In PDB	Thermus thermophilus
21	T	30S ribosomal protein S20	polymer	106	11722.1	1	UniProt (P62661) Pfam (PF01649) UniProt (by SIFTS) (P80380) In PDB	Thermus thermophilus
22	A, Z, D, M	MAGNESIUM ION	non-polymer		24.3	101	Chemie (MG)
23	A	POTASSIUM ION	non-polymer		39.1	12	Chemie (K)
24	A	(2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE	non-polymer		452.9	1	Chemie (D2C)
25	A	(2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE	non-polymer		509.6	1	Chemie (AB9)
26	D, N	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

D: 1 - 209 (UniProt: P80373)

PDB	External Database	Details
Gln 199	Asn 198	CONFLICT
Asn 201	Gln 200	CONFLICT

Contents of the asymmetric unit

Polymers	Number of chains	21
	Total formula weight	777850.5
Non-Polymers*	Number of molecules	117
	Total formula weight	4017.3
All*	Total formula weight	781867.8

*Water molecules are not included.