2EI8
FACTOR XA IN COMPLEX WITH THE INHIBITOR (1S,2R,4S)-N1-[(5-chloroindol-2-yl)carbonyl]-4-(N,N-dimethylcarbamoyl)-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor X, heavy chain | polymer | 233 | 26346.0 | 1 | UniProt (P00742) Pfam (PF00089) In PDB | Homo sapiens (human) | STUART FACTOR, STUART-PROWER FACTOR |
| 2 | B | Coagulation factor X, light chain | polymer | 54 | 5847.5 | 1 | UniProt (P00742) Pfam (PF14670) In PDB | Homo sapiens (human) | STUART FACTOR, STUART-PROWER FACTOR |
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | A | N-((1R,2S,5S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)-5-(DIMETHYLCARBAMOYL)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE | non-polymer | 543.1 | 1 | Chemie (DT8) | |||
| 5 | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32193.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 623.2 | |
| All* | Total formula weight | 32816.8 |
