2DLF
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 6.75
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S)-KAPPA (LIGHT CHAIN)) | polymer | 113 | 12386.9 | 1 | UniProt (P01631) Pfam (PF07686) In PDB | Mus musculus (house mouse) | |
| 2 | H | PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S) (HEAVY CHAIN)) | polymer | 124 | 14152.8 | 1 | UniProt (P01801) Pfam (PF07686) In PDB | Mus musculus (house mouse) | |
| 3 | L, H | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
L: 1 - 108 (UniProt: P01631)
H: 1 - 113 (UniProt: P01801)
| PDB | External Database | Details |
|---|---|---|
| Asn 17 | Asp 17 | conflict |
| Phe 96 | Tyr 101 | conflict |
| Ser 100 | Gly 105 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 24 | Ala 43 | conflict |
| Ala 49 | Gly 68 | conflict |
| Asn 52 | Ser 72 | conflict |
| Arg 76 | Ser 98 | conflict |
| Arg 77 | Ser 99 | conflict |
| Thr 82 | Ser 106 | conflict |
| Gly 94 | Pro 119 | conflict |
| Tyr 96 | Thr 121 | conflict |
| Tyr 97 | Thr 122 | conflict |
| His 98 | Gly 123 | conflict |
| Tyr 99 | - | insertion |
| Pro 100 | Ala 124 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26539.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 26731.9 |
