1ZZR
Rat nNOS D597N/M336V double mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nitric-oxide synthase, brain | polymer | 420 | 48579.2 | 2 | UniProt (P29476) Pfam (PF02898) In PDB | Rattus norvegicus (Norway rat) | NOS, type I, Neuronal NOS, N-NOS, nNOS, Constitutive NOS, NC-NOS, BNOS |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
4 | A, B | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
5 | A, B | L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE | non-polymer | 330.3 | 2 | Chemie (DP9) | |||
6 | A, B | trifluoroacetic acid | non-polymer | 114.0 | 2 | Chemie (TFA) | |||
7 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence modifications
A, B: 299 - 718 (UniProt: P29476)
PDB | External Database | Details |
---|---|---|
Val 336 | Met 336 | engineered mutation |
Asn 597 | Asp 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 97158.4 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2853.8 | |
All* | Total formula weight | 100012.2 |