1ZUA
Crystal Structure Of AKR1B10 Complexed With NADP+ And Tolrestat
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X | Aldo-keto reductase family 1 member B10 | polymer | 317 | 36209.7 | 1 | UniProt (O60218) Pfam (PF00248) In PDB | Homo sapiens (human) | Aldose reductase-like, ARL-1, Small intestine reductase, SI reductase, Aldose reductase-related protein, ARP, hARP |
2 | X | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
3 | X | TOLRESTAT | non-polymer | 357.3 | 1 | Chemie (TOL) | |||
4 | water | water | 18.0 | 411 | Chemie (HOH) |
Sequence modifications
X: 1 - 316 (UniProt: O60218)
PDB | External Database | Details |
---|---|---|
His 902 | - | expression tag |
Asn 313 | Asp 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36209.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1100.8 | |
All* | Total formula weight | 37310.4 |