1GII
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE CDK4 INHIBITOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CELL DIVISION PROTEIN KINASE 2 | polymer | 298 | 33925.4 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | CYCLIN DEPENDENT KINASE 2 |
2 | A | 1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-PYRIDIN-2-YL-UREA | non-polymer | 308.3 | 1 | Chemie (1PU) | |||
3 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDB | External Database | Details |
---|---|---|
His 82 | Phe 82 | engineered mutation |
Val 83 | Leu 83 | engineered mutation |
Thr 89 | Lys 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33925.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 308.3 | |
All* | Total formula weight | 34233.7 |