3OO2
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2.37 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF AN ALANINE RACEMASE (ALR) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS COL
Descriptor:Alanine racemase 1, SODIUM ION, BETA-MERCAPTOETHANOL, ...
Authors:Halavaty, A.S., Shuvalova, L., Minasov, G., Winsor, J., Dubrovska, I., Kwon, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-08-30
Release date:2010-10-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:2.37 Angstrom resolution crystal structure of an alanine racemase (alr) from Staphylococcus aureus subsp. aureus COL
TO BE PUBLISHED
4Y2W
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CRYSTAL STRUCTURE OF A THERMOSTABLE ALANINE RACEMASE FROM THERMOANAEROBACTER TENGCONGENSIS MB4
Descriptor:Alanine racemase 1, PHOSPHATE ION, ALANINE
Authors:Xu, X., Ju, J., Dong, H.
Deposit date:2015-02-10
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection
Plos One, 10, 2015
6G56
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APO-STRUCTURE OF THE ALANINE RACEMASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:Alanine racemase 1, SULFATE ION, GLYCEROL
Authors:Hoegl, A., Sieber, S.A., Schneider, S.
Deposit date:2018-03-29
Release date:2018-05-30
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10, 2018
6G58
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STRUCTURE OF THE ALANINE RACEMASE FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH A PYRIDOXAL 5' PHOSPHATE-DERIVATIVE
Descriptor:Alanine racemase 1, (6-but-3-ynyl-4-methyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, SODIUM ION, ...
Authors:Hoegl, A., Sieber, S.A., Schneider, S.
Deposit date:2018-03-29
Release date:2018-05-30
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10, 2018
6G59
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STRUCTURE OF THE ALANINE RACEMASE FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH AN PYRIDOXAL-6- PHOSPHATE DERIVATIVE
Descriptor:Alanine racemase 1, (6-ethynyl-4-methanoyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, SULFATE ION, ...
Authors:Hoegl, A., Sieber, S.A., Schneider, S.
Deposit date:2018-03-29
Release date:2018-05-30
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics.
Nat Chem, 10, 2018
2RJG
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
2RJH
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D-CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8T
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8U
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8V
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
3B8W
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-11-02
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
4A3Q
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THE 2.15 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS ALANINE RACEMASE
Descriptor:ALANINE RACEMASE 1, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
Authors:Scaletti, E.R., Luckner, S.R., Krause, K.L.
Deposit date:2011-10-04
Release date:2011-12-28
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Features and Kinetic Characterization of Alanine Racemase from Staphylococcus Aureus (Mu50)
Acta Crystallogr.,Sect.D, 68, 2012
4WR3
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Y274F ALANINE RACEMASE FROM E. COLI
Descriptor:Alanine racemase, biosynthetic, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Squire, C.J., Yosaatmadja, Y., Patrick, W.M.
Deposit date:2014-10-23
Release date:2015-11-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Y274F alanine racemase from E. coli
To Be Published
4XBJ
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Y274F ALANINE RACEMASE FROM E. COLI INHIBITED BY L-ALA-P
Descriptor:Alanine racemase, biosynthetic, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID, ...
Authors:Squire, C.J., Yosaatmadja, Y., Patrick, W.M.
Deposit date:2014-12-17
Release date:2015-12-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Y274F alanine racemase from E. coli
To Be Published
6A2F
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALANINE RACEMASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Alanine racemase, biosynthetic, MALONATE ION, ...
Authors:Dong, H., Li, S.
Deposit date:2018-06-11
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of biosynthetic alanine racemase from Pseudomonas aeruginosa
To Be Published
1AE4
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ALDEHYDE REDUCTASE COMPLEXED WITH COFACTOR AND INHIBITOR, ALPHA CARBON ATOMS ONLY
Descriptor:ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT
Authors:El-Kabbani, O.
Deposit date:1997-03-05
Release date:1998-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex.
Proteins, 29, 1997
1CWN
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CRYSTAL STRUCTURE OF PORCINE ALDEHYDE REDUCTASE HOLOENZYME
Descriptor:ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:El-Kabbani, O.
Deposit date:1996-07-30
Release date:1998-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of porcine aldehyde reductase at 2.0 angstrom resolution: Modeling an inhibitor in the active site of the enzyme.
Protein Pept.Lett., 3, 1996
2ALR
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ALDEHYDE REDUCTASE
Descriptor:ALDEHYDE REDUCTASE
Authors:El-Kabbani, O.
Deposit date:1994-09-06
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structures of human and porcine aldehyde reductase: an enzyme implicated in diabetic complications.
Acta Crystallogr.,Sect.D, 50, 1994
3H4G
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STRUCTURE OF ALDEHYDE REDUCTASE HOLOENZYME IN COMPLEX WITH POTENT ALDOSE REDUCTASE INHIBITOR FIDARESTAT: IMPLICATIONS FOR INHIBITOR BINDING AND SELECTIVITY
Descriptor:Alcohol dehydrogenase [NADP+], SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Carbone, V., El-Kabbani, O.
Deposit date:2009-04-20
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity
J.Med.Chem., 48, 2005