Mine: Updated entries

6M7Z
  • Download 6m7z
  • View 6m7z
Molmil generated image of 6m7z
A DIVERGENT KINASE LACKING THE GLYCINE-RICH LOOP REGULATES MEMBRANE ULTRASTRUCTURE OF THE TOXOPLASMA PARASITOPHOROUS VACUOLE
Descriptor:Bradyzoite pseudokinase 1, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Beraki, T., Borek, D.M., Reese, M.L.
Deposit date:2018-08-21
Release date:2018-10-17
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Divergent kinase regulates membrane ultrastructure of theToxoplasmaparasitophorous vacuole.
Proc. Natl. Acad. Sci. U.S.A., 2019
6MFQ
  • Download 6mfq
  • View 6mfq
Molmil generated image of 6mfq
CRYSTAL STRUCTURE OF A PMS2 VARIANT
Descriptor:Mismatch repair endonuclease PMS2
Authors:D'Arcy, B.M., Prakash, A.
Deposit date:2018-09-11
Release date:2019-02-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene.
Hum. Mutat., 40, 2019
6MW6
  • Download 6mw6
  • View 6mw6
Molmil generated image of 6mw6
ANTIMICROBIAL LASSO PEPTIDE CITROCIN
Descriptor:Citrocin
Authors:Link, A.J., Cheung-Lee, W.L.
Deposit date:2018-10-29
Release date:2019-03-13
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Discovery and structure of the antimicrobial lasso peptide citrocin.
J. Biol. Chem., 2019
6MZX
  • Download 6mzx
  • View 6mzx
Molmil generated image of 6mzx
CRYO-EM STRUCTURE OF THE HO BMC SHELL: ICOSAHEDRAL RECONSTRUCTION (MAIN POPULATION)
Descriptor:Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein HO-5815, Microcompartments protein HO-5816
Authors:Greber, B.J., Sutter, M., Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 2019
6N7Q
  • Download 6n7q
  • View 6n7q
Molmil generated image of 6n7q
PLASMODIUM FALCIPARUM FVO APICAL MEMBRANE ANTIGEN 1 (AMA1) BOUND TO CYCLISED RON2 PEPTIDE
Descriptor:Apical membrane antigen-1, RON2 peptide
Authors:McGowan, S., Drinkwater, N.
Deposit date:2018-11-28
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
ChemMedChem, 14, 2019
6N87
  • Download 6n87
  • View 6n87
Molmil generated image of 6n87
PLASMODIUM FALCIPARUM FVO APICAL MEMBRANE ANTIGEN 1 (AMA1) BOUND TO MTSL SPIN-LABELLED CYCLISED RON2 PEPTIDE
Descriptor:Apical membrane antigen-1, backbone-cyclised peptide bcRON2hp, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:McGowan, S., Drinkwater, N.
Deposit date:2018-11-28
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.588 Å)
Cite:Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
ChemMedChem, 14, 2019
6NBB
  • Download 6nbb
  • View 6nbb
Molmil generated image of 6nbb
HORSE LIVER ALCOHOL DEHYDROGENASE DETERMINED USING SINGLE-PARTICLE CRYO-EM AT 200 KEV
Descriptor:Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2018-12-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.
Nat Commun, 10, 2019
6NBC
  • Download 6nbc
  • View 6nbc
Molmil generated image of 6nbc
HUMAN METHEMOGLOBIN STATE 1 DETERMINED USING SINGLE-PARTICLE CRYO-EM AT 200 KEV
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2018-12-06
Release date:2019-03-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.
Nat Commun, 10, 2019
6NBD
  • Download 6nbd
  • View 6nbd
Molmil generated image of 6nbd
HUMAN METHEMOGLOBIN STATE 2 DETERMINED USING SINGLE-PARTICLE CRYO-EM AT 200 KEV
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Herzik Jr., M.A., Wu, M., Lander, G.C.
Deposit date:2018-12-06
Release date:2019-02-13
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.
Nat Commun, 10, 2019
6ND6
  • Download 6nd6
  • View 6nd6
Molmil generated image of 6nd6
CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ERYTHROMYCIN AND BOUND TO MRNA AND A-, P-, AND E-SITE TRNAS AT 2.85A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Svetlov, M.S., Plessa, E., Chen, C.-W., Bougas, A., Krokidis, M.G., Dinos, G.P., Polikanov, Y.S.
Deposit date:2018-12-13
Release date:2019-02-20
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA, 2019
6NE0
  • Download 6ne0
  • View 6ne0
Molmil generated image of 6ne0
STRUCTURE OF DOUBLE-STRANDED TARGET DNA ENGAGED CSY COMPLEX FROM PSEUDOMONAS AERUGINOSA (PA-14)
Descriptor:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
Authors:Chowdhury, S., Rollins, M.F., Carter, J., Golden, S.M., Miettinen, H.M., Santiago-Frangos, A., Faith, D., Lawrence, M.C., Wiedenheft, B., Lander, G.C.
Deposit date:2018-12-15
Release date:2018-12-26
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry
Mol.Cell, 2019
6NHW
  • Download 6nhw
  • View 6nhw
Molmil generated image of 6nhw
STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 - DIMER OF TRIMER
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Fu, Q., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NHY
  • Download 6nhy
  • View 6nhy
Molmil generated image of 6nhy
STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 MUTANT (G217Y) - TRIMER ONLY
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H., Liu, Z.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NIR
  • Download 6nir
  • View 6nir
Molmil generated image of 6nir
CRYSTAL STRUCTURE OF A GII.4 NOROVIRUS HOV PROTEASE
Descriptor:HOV protease, HOV protease fragment
Authors:Prasad, B.V.V., Hu, L.
Deposit date:2018-12-31
Release date:2019-01-23
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site.
J. Virol., 93, 2019
6NJ9
  • Download 6nj9
  • View 6nj9
Molmil generated image of 6nj9
ACTIVE STATE DOT1L BOUND TO THE H2B-UBIQUITINATED NUCLEOSOME, 2-TO-1 COMPLEX
Descriptor:Histone H4, Histone H2A type 1, Histone H2B 1.1, ...
Authors:Worden, E.J., Hoffmann, N.A., Wolberger, C.
Deposit date:2019-01-02
Release date:2019-02-20
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6NMB
  • Download 6nmb
  • View 6nmb
Molmil generated image of 6nmb
TRANEXAMIC ACID IS AN ACTIVE SITE INHIBITOR OF UROKINASE PLASMINOGEN ACTIVATOR
Descriptor:Urokinase-type plasminogen activator, NITRATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:Law, R.H.P., Wu, G.
Deposit date:2019-01-10
Release date:2019-03-06
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tranexamic acid is an active site inhibitor of urokinase plasminogen activator
Blood Adv, 3, 2019
6NMF
  • Download 6nmf
  • View 6nmf
Molmil generated image of 6nmf
SFX STRUCTURE OF REDUCED CYTOCHROME C OXIDASE AT ROOM TEMPERATURE
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Rousseau, D.L., Yeh, S.-R., Ishigami, I.
Deposit date:2019-01-10
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Snapshot of an oxygen intermediate in the catalytic reaction of cytochromecoxidase.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NMP
  • Download 6nmp
  • View 6nmp
Molmil generated image of 6nmp
SFX STRUCTURE OF OXIDIZED CYTOCHROME C OXIDASE AT ROOM TEMPERATURE
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase subunit 3, ...
Authors:Rousseau, D.L., Yeh, S.-R., Ishigami, I.
Deposit date:2019-01-11
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Snapshot of an oxygen intermediate in the catalytic reaction of cytochromecoxidase.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NNA
  • Download 6nna
  • View 6nna
Molmil generated image of 6nna
HUMAN FATTY ACID SYNTHASE PSI/KR TRI-DOMAIN WITH NADPH AND COMPOUND 22
Descriptor:Fatty acid synthase,Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {4-[4-(1,3-benzoxazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}(1-hydroxycyclopropyl)methanone, ...
Authors:Toms, A.V., Martin, M.W.
Deposit date:2019-01-14
Release date:2019-02-20
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Bioorg. Med. Chem. Lett., 29, 2019
6NOG
  • Download 6nog
  • View 6nog
Molmil generated image of 6nog
POISED-STATE DOT1L BOUND TO THE H2B-UBIQUITINATED NUCLEOSOME
Descriptor:Histone H3.2, Histone H4, Histone H2A type 1, ...
Authors:Worden, E.J., Hoffmann, N.A., Wolberger, C.
Deposit date:2019-01-16
Release date:2019-02-20
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6NQA
  • Download 6nqa
  • View 6nqa
Molmil generated image of 6nqa
ACTIVE STATE DOT1L BOUND TO THE H2B-UBIQUITINATED NUCLEOSOME, 1-TO-1 COMPLEX
Descriptor:601 DNA Strand 1, 601 DNA Strand 2, Histone H4, ...
Authors:Worden, E.J., Hoffmann, N.A., Wolberger, C.
Deposit date:2019-01-19
Release date:2019-02-20
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
6NT5
  • Download 6nt5
  • View 6nt5
Molmil generated image of 6nt5
CRYO-EM STRUCTURE OF FULL-LENGTH HUMAN STING IN THE APO STATE
Descriptor:Stimulator of interferon protein
Authors:Shang, G., Zhang, C., Chen, Z.J., Bai, X., Zhang, X.
Deposit date:2019-01-28
Release date:2019-03-06
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 2019
6NT6
  • Download 6nt6
  • View 6nt6
Molmil generated image of 6nt6
CRYO-EM STRUCTURE OF FULL-LENGTH CHICKEN STING IN THE APO STATE
Descriptor:Stimulator of interferon genes protein
Authors:Shang, G., Zhang, C., Chen, Z.J., Bai, X., Zhang, X.
Deposit date:2019-01-28
Release date:2019-03-06
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 2019
6NT7
  • Download 6nt7
  • View 6nt7
Molmil generated image of 6nt7
CRYO-EM STRUCTURE OF FULL-LENGTH CHICKEN STING IN THE CGAMP-BOUND DIMERIC STATE
Descriptor:Stimulator of interferon genes protein, cGAMP
Authors:Shang, G., Zhang, C., Chen, Z.J., Bai, X., Zhang, X.
Deposit date:2019-01-28
Release date:2019-03-06
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 2019
6NT8
  • Download 6nt8
  • View 6nt8
Molmil generated image of 6nt8
CRYO-EM STRUCTURE OF FULL-LENGTH CHICKEN STING IN THE CGAMP-BOUND TETRAMERIC STATE
Descriptor:Stimulator of interferon genes protein, cGAMP
Authors:Shang, G., Zhang, C., Chen, Z.J., Bai, X., Zhang, X.
Deposit date:2019-01-28
Release date:2019-03-06
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 2019