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6CTY
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BU of 6cty by Molmil
Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and malate at 2.4 A resolution
Descriptor: D-MALATE, Dihydroorotase, ZINC ION
Authors:Lipowska, J, Shabalin, I.G, Winsor, J, Woinska, M, Cooper, D.R, Kwon, K, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-03-23
Release date:2018-04-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
8WQ9
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BU of 8wq9 by Molmil
Crystal structure of dihydropyrimidinase complexed with gamma-aminobutyric acid
Descriptor: D-hydantoinase/dihydropyrimidinase, GAMMA-AMINO-BUTANOIC ACID, ZINC ION
Authors:Huang, Y.H, Huang, C.Y.
Deposit date:2023-10-11
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter gamma-aminobutyric acid (GABA).
Biochem.Biophys.Res.Commun., 692, 2024
2AQO
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BU of 2aqo by Molmil
Crystal structure of E. coli Isoaspartyl Dipeptidase Mutant E77Q
Descriptor: Isoaspartyl dipeptidase, ZINC ION
Authors:Marti-Arbona, R, Thoden, J.B, Holden, H.M, Raushel, F.M.
Deposit date:2005-08-18
Release date:2005-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase.
Bioorg.Chem., 33, 2005
7X68
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BU of 7x68 by Molmil
CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone
Descriptor: (3aR,5S,8R,8aR,9aR)-5,8a-dimethyl-3-methylidene-8-oxidanyl-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one, Dihydropyrimidinase-related protein 2, SODIUM ION
Authors:Zhang, S.D, Ma, Y.F, Zhang, J.
Deposit date:2022-03-06
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone
To Be Published
4M51
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BU of 4m51 by Molmil
Crystal structure of amidohydrolase nis_0429 (ser145ala mutant) from nitratiruptor sp. sb155-2
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Amidohydrolase family protein, BENZOIC ACID, ...
Authors:Patskovsky, Y, Toro, R, Gobble, A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-08-07
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes.
Biochemistry, 52, 2013
8DNM
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BU of 8dnm by Molmil
Human Brain Dihydropyrimidinase-related protein 2
Descriptor: Dihydropyrimidinase-related protein 2
Authors:Tringides, M.L.
Deposit date:2022-07-11
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
5X1C
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BU of 5x1c by Molmil
Crystal Structure of Human CRMP-2 without C-terminal Tail
Descriptor: Dihydropyrimidinase-related protein 2
Authors:Nitta, R, Tomabechi, Y, Aoki, M, Shirouzu, M.
Deposit date:2017-01-25
Release date:2017-09-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural basis for CRMP2-induced axonal microtubule formation
Sci Rep, 7, 2017
4LH8
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BU of 4lh8 by Molmil
Triazine hydrolase from Arthobacter aurescens modified for maximum expression in E.coli
Descriptor: Triazine hydrolase, ZINC ION
Authors:Jackson, C.J, Coppin, C.W, Alexandrov, A, Wilding, M, Liu, J.-W, Ubels, J, Paks, M, Carr, P.D, Newman, J, Russell, R.J, Field, M, Weik, M, Oakeshott, J.G, Scott, C.
Deposit date:2013-07-01
Release date:2014-05-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization.
Appl.Environ.Microbiol., 80, 2014
4LFY
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BU of 4lfy by Molmil
Crystal structure of a dihydroorotase from Burkholderia cenocepacia J2315
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Dihydroorotase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-06-27
Release date:2013-07-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a dihydroorotase from Burkholderia cenocepacia J2315
To be Published
4CNU
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BU of 4cnu by Molmil
CRYSTAL STRUCTURE OF WT HUMAN CRMP-4 from lattice translocation
Descriptor: DIHYDROPYRIMIDINASE-LIKE 3
Authors:Ponnusamy, R, Lebedev, A, Lohkamp, B.
Deposit date:2014-01-24
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Acta Crystallogr.,Sect.D, 70, 2014
4CNT
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BU of 4cnt by Molmil
CRYSTAL STRUCTURE OF WT HUMAN CRMP-4
Descriptor: 1,2-ETHANEDIOL, DIHYDROPYRIMIDINASE-LIKE 3, SODIUM ION
Authors:Ponnusamy, R, Lohkamp, B.
Deposit date:2014-01-24
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Acta Crystallogr.,Sect.D, 70, 2014
5XGW
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BU of 5xgw by Molmil
Isoaspartyl dipeptidase from Colwellia psychrerythraea strain 34H
Descriptor: Isoaspartyl dipeptidase, ZINC ION
Authors:Lee, J.H, Lee, C.W, Park, S.H.
Deposit date:2017-04-18
Release date:2018-06-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure and functional characterization of an isoaspartyl dipeptidase (CpsIadA) from Colwellia psychrerythraea strain 34H.
PLoS ONE, 12, 2017
7U5K
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BU of 7u5k by Molmil
Cryo-EM Structure of DPYSL2
Descriptor: Dihydropyrimidinase-related protein 2
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2022-03-02
Release date:2022-12-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
7UOF
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BU of 7uof by Molmil
Dihydroorotase from M. jannaschii
Descriptor: Dihydroorotase, ZINC ION
Authors:Vitali, J, Nix, J.C, Newman, H.E, Colaneri, M.J.
Deposit date:2022-04-12
Release date:2022-08-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Methanococcus jannaschii dihydroorotase.
Proteins, 91, 2023
5LP3
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BU of 5lp3 by Molmil
Three tetrameric rings of Isoaspartyl Dipeptidase fitted in an EM volume.
Descriptor: Isoaspartyl dipeptidase
Authors:Garcia-Seisdedos, H, Empereur-Mot, C, Elad, N, Levy, E.D.
Deposit date:2016-08-11
Release date:2017-07-26
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (10.5 Å)
Cite:Proteins evolve on the edge of supramolecular self-assembly.
Nature, 548, 2017
5LXX
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BU of 5lxx by Molmil
High-resolution structure of human collapsin response mediator protein 2
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydropyrimidinase-related protein 2, SULFATE ION
Authors:Myllykoski, M, Hensley, K, Kursula, P.
Deposit date:2016-09-23
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility.
Amino Acids, 49, 2017
4YIW
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BU of 4yiw by Molmil
DIHYDROOROTASE FROM BACILLUS ANTHRACIS WITH SUBSTRATE BOUND
Descriptor: Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ZINC ION
Authors:Lei, H, Santarsiero, B.D, Rice, A.J, Lee, H, Johnson, M.E.
Deposit date:2015-03-02
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase).
Bioorg.Med.Chem., 24, 2016
5E5C
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BU of 5e5c by Molmil
Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1
Descriptor: D-hydantoinase/dihydropyrimidinase, ZINC ION
Authors:Huang, C.C, Huang, Y.H, Hsieh, Y.C, Tzeng, C.T, Chen, C.J, Huang, C.Y.
Deposit date:2015-10-08
Release date:2016-09-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer
Biochem.Biophys.Res.Commun., 478, 2016
5HME
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BU of 5hme by Molmil
Crystal structure of Triazine Hydrolase variant (P214T/Y215H)
Descriptor: Triazine hydrolase, ZINC ION
Authors:Sugrue, E, Carr, P.D, Jackson, C.J.
Deposit date:2016-01-16
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5HMD
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BU of 5hmd by Molmil
Crystal structure of triazine hydrolase variant (Y215H/E241Q)
Descriptor: Triazine hydrolase, ZINC ION
Authors:Sugrue, E, Carr, P.D, Jackson, C.J.
Deposit date:2016-01-16
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5HMF
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BU of 5hmf by Molmil
Crystal structure of triazine hydrolase variant (P214T/Y215H/E241Q)
Descriptor: Triazine hydrolase, ZINC ION
Authors:Sugrue, E, Carr, P.D, Jackson, C.J.
Deposit date:2016-01-16
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
4V1Y
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BU of 4v1y by Molmil
The structure of the hexameric atrazine chlorohydrolase, AtzA
Descriptor: 1,2-ETHANEDIOL, ATRAZINE CHLOROHYDROLASE, CHLORIDE ION, ...
Authors:Peat, T.S, Newman, J, Balotra, S, Lucent, D, Warden, A.C, Scott, C.
Deposit date:2014-10-04
Release date:2015-03-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Hexameric Atrazine Chlorohydrolase Atza.
Acta Crystallogr.,Sect.D, 71, 2015
5MKV
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BU of 5mkv by Molmil
Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2) residues 13-516
Descriptor: 1,2-ETHANEDIOL, Dihydropyrimidinase-related protein 2
Authors:Sethi, R, Zheng, Y, Krojer, T, Velupillai, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ahmed, A.A, von Delft, F.
Deposit date:2016-12-05
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
3GRI
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BU of 3gri by Molmil
The Crystal Structure of a Dihydroorotase from Staphylococcus aureus
Descriptor: CALCIUM ION, CHLORIDE ION, Dihydroorotase, ...
Authors:Brunzelle, J.S, Wawrzak, Z, Skarina, T, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-03-25
Release date:2009-05-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of a Dihydroorotase from Staphylococcus aureus
To be Published
4V1X
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BU of 4v1x by Molmil
The structure of the hexameric atrazine chlorohydrolase, AtzA
Descriptor: ATRAZINE CHLOROHYDROLASE, DI(HYDROXYETHYL)ETHER, FE (III) ION
Authors:Peat, T.S, Newman, J, Balotra, S, Lucent, D, Warden, A.C, Scott, C.
Deposit date:2014-10-04
Release date:2015-03-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of the Hexameric Atrazine Chlorohydrolase Atza.
Acta Crystallogr.,Sect.D, 71, 2015

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