1BGX
 
 | | TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB | | 分子名称: | TAQ DNA POLYMERASE, TP7 MAB | | 著者 | Murali, R, Sharkey, D.J, Daiss, J.L, Krishna Murthy, H.M. | | 登録日 | 1998-06-02 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1EXN
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1TAQ
 | | STRUCTURE OF TAQ DNA POLYMERASE | | 分子名称: | 2-O-octyl-beta-D-glucopyranose, TAQ DNA POLYMERASE, ZINC ION | | 著者 | Kim, Y, Eom, S.H, Wang, J, Lee, D.-S, Suh, S.W, Steitz, T.A. | | 登録日 | 1996-06-04 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of Thermus aquaticus DNA polymerase.
Nature, 376, 1995
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1TAU
 | | TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX | | 分子名称: | 2-O-octyl-beta-D-glucopyranose, DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), ... | | 著者 | Eom, S.H, Wang, J, Steitz, T.A. | | 登録日 | 1996-06-17 | | 公開日 | 1997-04-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of Taq ploymerase with DNA at the polymerase active site.
Nature, 382, 1996
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1UT5
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1UT8
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1XO1
 | | T5 5'-EXONUCLEASE MUTANT K83A | | 分子名称: | 5'-EXONUCLEASE | | 著者 | Ceska, T.A, Suck, D, Sayers, J.R. | | 登録日 | 1998-11-19 | | 公開日 | 1999-04-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.
Proc.Natl.Acad.Sci.USA, 96, 1999
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3ZD8
 | | Potassium bound structure of E. coli ExoIX in P1 | | 分子名称: | POTASSIUM ION, PROTEIN XNI | | 著者 | Anstey-Gilbert, C.S, Hemsworth, G.R, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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3ZD9
 | | Potassium bound structure of E. coli ExoIX in P21 | | 分子名称: | POTASSIUM ION, PROTEIN XNI | | 著者 | Anstey-Gilbert, C.S, Hemsworth, G.R, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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3ZDA
 | | Structure of E. coli ExoIX in complex with a fragment of the Flap1 DNA oligonucleotide, potassium and magnesium | | 分子名称: | 5'-D(*AP*AP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP)-3', MAGNESIUM ION, ... | | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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3ZDB
 | | Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, di-magnesium and potassium | | 分子名称: | 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ... | | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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3ZDC
 | | Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, potassium and calcium | | 分子名称: | 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ... | | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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3ZDD
 | | Structure of E. coli ExoIX in complex with the palindromic 5ov6 oligonucleotide and potassium | | 分子名称: | 1,2-ETHANEDIOL, 5OV6 DNA, ISOPROPYL ALCOHOL, ... | | 著者 | Flemming, C.S, Hemsworth, G.R, Anstey-Gilbert, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2019-02-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of Escherichia coli ExoIX--implications for DNA binding and catalysis in flap endonucleases.
Nucleic Acids Res., 41, 2013
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3ZDE
 | | Potassium free structure of E. coli ExoIX | | 分子名称: | PROTEIN XNI | | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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5HML
 | | Crystal Structure of T5 D15 Protein Co-crystallized with Metal Ions | | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Flemming, C.S, Feng, M, Sedelnikova, S.E, Zhang, J, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2016-01-16 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
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5HMM
 | | Crystal Structure of T5 D15 Protein Co-crystallized with Metal Ions | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Exodeoxyribonuclease, ... | | 著者 | Flemming, C.S, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2016-01-16 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
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5HNK
 | | Crystal structure of T5Fen in complex intact substrate and metal ions. | | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*C)-3'), Exodeoxyribonuclease, GLYCEROL, ... | | 著者 | Almalki, F.A, Feng, M, Zhang, J, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2016-01-18 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
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5HP4
 | | Crystal structure bacteriohage T5 D15 flap endonuclease (D155K) pseudo-enzyme-product complex with DNA and metal ions | | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*AP*TP*CP*TP*AP*TP*AP*TP*GP*CP*CP*AP*TP*CP*GP*G)-3'), Exodeoxyribonuclease, ... | | 著者 | Almalki, F.A, Zhang, J, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.A. | | 登録日 | 2016-01-20 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
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6C33
 | | Mycobacterium smegmatis DNA flap endonuclease | | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | | 登録日 | 2018-01-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
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6C34
 | | Mycobacterium smegmatis DNA flap endonuclease mutant D125N | | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | | 登録日 | 2018-01-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
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6C35
 | | Mycobacterium smegmatis flap endonuclease mutant D148N | | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | | 登録日 | 2018-01-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
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6C36
 | | Mycobacterium smegmatis flap endonuclease mutant D208N | | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION, PHOSPHATE ION | | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | | 登録日 | 2018-01-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.
Nucleic Acids Res., 46, 2018
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6VDE
 | | Full-length M. smegmatis Pol1 | | 分子名称: | DNA polymerase I, MANGANESE (II) ION | | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | | 登録日 | 2019-12-24 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.713 Å) | | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme.
Nucleic Acids Res., 48, 2020
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