Summary
| Title: | Crystal structure of PT2399 bound to HIF2a-B*:ARNT-B* complex |
| Citation: | Cho, H.,Du, X.,Rizzi, J.P.,Liberzon, E.,Chakraborty, A.A.,Gao, W.,Carvo, I.,Signoretti, S.,Bruick, R.K.,Josey, J.A.,Wallace, E.M.,Kaelin, W.G. On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models. Nature, 539:107-111, 2016 PubMed: 27595393DOI: 10.1038/nature19795 |
| Experimental method: | X-RAY DIFFRACTION (2.2 Å) |
| Deposition date: | 2016-08-16 |
| Release date: | 2016-08-31 |
| Obsoletion date: | 2017-01-25 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 5t0t.cif.gz Display(56.64 KB) 5t0t.cif | ||
| PDBx/mmJSON | no-atom | 5t0t-noatom.json.gz Display (Header)(10.71 KB) 5t0t-noatom.json | |
| PDBML | all | 5t0t.xml.gz Display(72.58 KB) 5t0t.xml | |
| PDB | pdb5t0t.ent.gz Display(43.54 KB) pdb5t0t.ent | ||
| Structure factors | r5t0tsf.ent.gz Display(494.26 KB) r5t0tsf.ent | ||
