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6QCZ

MloK1 model from single particle analysis of 2D crystals, class 3 (intermediate extended conformation)

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0000166molecular_functionnucleotide binding
A0005216molecular_functionmonoatomic ion channel activity
A0005222molecular_functionintracellularly cAMP-activated cation channel activity
A0005223molecular_functionintracellularly cGMP-activated cation channel activity
A0005267molecular_functionpotassium channel activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006813biological_processpotassium ion transport
A0016020cellular_componentmembrane
A0017071cellular_componentintracellular cyclic nucleotide activated cation channel complex
A0030552molecular_functioncAMP binding
A0030553molecular_functioncGMP binding
A0034220biological_processmonoatomic ion transmembrane transport
A0042802molecular_functionidentical protein binding
A0044877molecular_functionprotein-containing complex binding
A0055085biological_processtransmembrane transport
A0071805biological_processpotassium ion transmembrane transport
B0000166molecular_functionnucleotide binding
B0005216molecular_functionmonoatomic ion channel activity
B0005222molecular_functionintracellularly cAMP-activated cation channel activity
B0005223molecular_functionintracellularly cGMP-activated cation channel activity
B0005267molecular_functionpotassium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006813biological_processpotassium ion transport
B0016020cellular_componentmembrane
B0017071cellular_componentintracellular cyclic nucleotide activated cation channel complex
B0030552molecular_functioncAMP binding
B0030553molecular_functioncGMP binding
B0034220biological_processmonoatomic ion transmembrane transport
B0042802molecular_functionidentical protein binding
B0044877molecular_functionprotein-containing complex binding
B0055085biological_processtransmembrane transport
B0071805biological_processpotassium ion transmembrane transport
C0000166molecular_functionnucleotide binding
C0005216molecular_functionmonoatomic ion channel activity
C0005222molecular_functionintracellularly cAMP-activated cation channel activity
C0005223molecular_functionintracellularly cGMP-activated cation channel activity
C0005267molecular_functionpotassium channel activity
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0006813biological_processpotassium ion transport
C0016020cellular_componentmembrane
C0017071cellular_componentintracellular cyclic nucleotide activated cation channel complex
C0030552molecular_functioncAMP binding
C0030553molecular_functioncGMP binding
C0034220biological_processmonoatomic ion transmembrane transport
C0042802molecular_functionidentical protein binding
C0044877molecular_functionprotein-containing complex binding
C0055085biological_processtransmembrane transport
C0071805biological_processpotassium ion transmembrane transport
D0000166molecular_functionnucleotide binding
D0005216molecular_functionmonoatomic ion channel activity
D0005222molecular_functionintracellularly cAMP-activated cation channel activity
D0005223molecular_functionintracellularly cGMP-activated cation channel activity
D0005267molecular_functionpotassium channel activity
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006813biological_processpotassium ion transport
D0016020cellular_componentmembrane
D0017071cellular_componentintracellular cyclic nucleotide activated cation channel complex
D0030552molecular_functioncAMP binding
D0030553molecular_functioncGMP binding
D0034220biological_processmonoatomic ion transmembrane transport
D0042802molecular_functionidentical protein binding
D0044877molecular_functionprotein-containing complex binding
D0055085biological_processtransmembrane transport
D0071805biological_processpotassium ion transmembrane transport
PDBデータベースに由来する情報
site_idAC1
残基数8
詳細binding site for residue K A 401
鎖名残基
ATHR175
ATHR176
BTHR175
BTHR176
CTHR175
CTHR176
DTHR175
DTHR176

site_idAC2
残基数8
詳細binding site for residue K D 401
鎖名残基
ATYR178
BGLY177
BTYR178
CGLY177
CTYR178
DGLY177
DTYR178
AGLY177

UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00888
残基数17
詳細CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. ICrIGEpGDrMFFVveG
鎖名残基詳細
AILE262-GLY278

site_idPS00889
残基数18
詳細CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGEmALisgep......RSAtVsA
鎖名残基詳細
APHE296-ALA313

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数732
詳細TOPO_DOM: Cytoplasmic
鎖名残基詳細
AMET1-PRO12
CLYS62-LYS74
CTHR113-LEU129
CALA211-ALA355
DMET1-PRO12
DLYS62-LYS74
DTHR113-LEU129
DALA211-ALA355
ALYS62-LYS74
ATHR113-LEU129
AALA211-ALA355
BMET1-PRO12
BLYS62-LYS74
BTHR113-LEU129
BALA211-ALA355
CMET1-PRO12

site_idSWS_FT_FI2
残基数68
詳細TRANSMEM: Helical; Name=Segment S1
鎖名残基詳細
ALEU13-ILE30
BLEU13-ILE30
CLEU13-ILE30
DLEU13-ILE30

site_idSWS_FT_FI3
残基数84
詳細TOPO_DOM: Periplasmic
鎖名残基詳細
APRO31-ARG38
DPRO31-ARG38
DGLU151-SER161
DTHR181-SER185
AGLU151-SER161
ATHR181-SER185
BPRO31-ARG38
BGLU151-SER161
BTHR181-SER185
CPRO31-ARG38
CGLU151-SER161
CTHR181-SER185

site_idSWS_FT_FI4
残基数88
詳細TRANSMEM: Helical; Name=Segment S2
鎖名残基詳細
ALEU39-LEU61
BLEU39-LEU61
CLEU39-LEU61
DLEU39-LEU61

site_idSWS_FT_FI5
残基数76
詳細TRANSMEM: Helical; Name=Segment S3
鎖名残基詳細
AILE75-SER94
BILE75-SER94
CILE75-SER94
DILE75-SER94

site_idSWS_FT_FI6
残基数68
詳細TRANSMEM: Helical; Name=Segment S4
鎖名残基詳細
APRO95-SER112
BPRO95-SER112
CPRO95-SER112
DPRO95-SER112

site_idSWS_FT_FI7
残基数80
詳細TRANSMEM: Helical; Name=Segment S5
鎖名残基詳細
AILE130-ILE150
BILE130-ILE150
CILE130-ILE150
DILE130-ILE150

site_idSWS_FT_FI8
残基数72
詳細INTRAMEM: Pore-forming
鎖名残基詳細
AILE162-ASP180
BILE162-ASP180
CILE162-ASP180
DILE162-ASP180

site_idSWS_FT_FI9
残基数96
詳細TRANSMEM: Helical; Name=Segment S6
鎖名残基詳細
APHE186-LEU210
BPHE186-LEU210
CPHE186-LEU210
DPHE186-LEU210

site_idSWS_FT_FI10
残基数12
詳細BINDING: BINDING => ECO:0007744|PDB:1VP6
鎖名残基詳細
AGLY297
DGLY297
DARG307
DARG348
AARG307
AARG348
BGLY297
BARG307
BARG348
CGLY297
CARG307
CARG348

218853

件を2024-04-24に公開中

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