6OM4

The structure of Microcin C7 biosynthetic enzyme MccB in complex with N-formylated MccA

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Functional Information from GO Data

ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0046872molecular_functionmetal ion binding
A0008641molecular_functionubiquitin-like modifier activating enzyme activity
B0005524molecular_functionATP binding
B0046872molecular_functionmetal ion binding
B0008641molecular_functionubiquitin-like modifier activating enzyme activity
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Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC14binding site for residue ZN A 401
ChainResidue
ACYS257
ACYS260
ACYS343
ACYS346

AC25binding site for residue MG A 402
ChainResidue
APOP403
AHOH516
AHOH518
AHOH585
AHOH591

AC318binding site for residue POP A 403
ChainResidue
AASN154
AARG157
AGLN158
ALYS170
AMG402
AMG404
AHOH518
AHOH521
AHOH524
AHOH532
AHOH533
AHOH568
AHOH585
AHOH591
AHOH623
AHOH627
BARG94
CND7101

AC45binding site for residue MG A 404
ChainResidue
APOP403
AHOH532
AHOH568
AHOH623
CND7101

AC54binding site for residue ZN B 401
ChainResidue
BCYS257
BCYS260
BCYS343
BCYS346

AC65binding site for residue MG B 402
ChainResidue
BGLU151
BPOP404
BHOH504
BHOH587
BHOH589

AC75binding site for residue MG B 403
ChainResidue
BPOP404
BHOH526
BHOH545
BHOH576
DND7101

AC815binding site for residue POP B 404
ChainResidue
AARG94
BASN154
BARG157
BGLN158
BLYS170
BMG402
BMG403
BHOH526
BHOH528
BHOH545
BHOH576
BHOH584
BHOH587
BHOH589
DND7101

AC919binding site for residue ND7 C 101
ChainResidue
AGLY122
AGLY124
AGLY125
AARG157
AGLN158
ALYS170
ALEU192
AASN193
AILE194
ASER212
AALA213
AHIS215
ATYR239
APOP403
AMG404
AHOH532
AHOH568
BGLU273
BHOH571

AD117binding site for residue ND7 D 101
ChainResidue
BGLY122
BGLY124
BGLY125
BASN147
BARG157
BGLN158
BLYS170
BLEU192
BILE194
BSER212
BALA213
BHIS215
BTYR239
BMG403
BPOP404
BHOH526
BHOH545

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
FME_6om4_D_115N-FORMYLMETHIONINE binding site
ChainResidueligand
AGLY22-GLY23FME: N-FORMYLMETHIONINE
AGLU26FME: N-FORMYLMETHIONINE
BVAL240FME: N-FORMYLMETHIONINE
BILE243FME: N-FORMYLMETHIONINE
BVAL245FME: N-FORMYLMETHIONINE
BVAL264FME: N-FORMYLMETHIONINE
BARG322-GLY324FME: N-FORMYLMETHIONINE
BTRP326FME: N-FORMYLMETHIONINE
BHIS333FME: N-FORMYLMETHIONINE
BGLN335FME: N-FORMYLMETHIONINE
DARG2-THR3FME: N-FORMYLMETHIONINE

POP_6om4_B_40412PYROPHOSPHATE 2- binding site
ChainResidueligand
AARG94POP: PYROPHOSPHATE 2-
BGLY124-GLY125POP: PYROPHOSPHATE 2-
BASP148POP: PYROPHOSPHATE 2-
BGLU151POP: PYROPHOSPHATE 2-
BTHR153-ASN154POP: PYROPHOSPHATE 2-
BARG157-GLN158POP: PYROPHOSPHATE 2-
BLYS170POP: PYROPHOSPHATE 2-
BLYS287POP: PYROPHOSPHATE 2-
BTHR290POP: PYROPHOSPHATE 2-

ND7_6om4_C_101265'-O-[(S)-amino(hydroxy)phosphoryl]adenosine binding site
ChainResidueligand
ALEU121-ILE126ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
AILE145-ASP148ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
AARG157-GLN158ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
ALYS170ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
ALEU192-ASN195ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
ASER212-PRO216ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
ALEU219ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
ATYR239ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
CALA6-ASP7ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine

POP_6om4_A_40312PYROPHOSPHATE 2- binding site
ChainResidueligand
AGLY124-GLY125POP: PYROPHOSPHATE 2-
AASP148POP: PYROPHOSPHATE 2-
AGLU151POP: PYROPHOSPHATE 2-
ATHR153-ASN154POP: PYROPHOSPHATE 2-
AARG157-GLN158POP: PYROPHOSPHATE 2-
ALYS170POP: PYROPHOSPHATE 2-
ALYS287POP: PYROPHOSPHATE 2-
ATHR290POP: PYROPHOSPHATE 2-
BARG94POP: PYROPHOSPHATE 2-

FME_6om4_C_115N-FORMYLMETHIONINE binding site
ChainResidueligand
AVAL240FME: N-FORMYLMETHIONINE
AILE243FME: N-FORMYLMETHIONINE
AVAL245FME: N-FORMYLMETHIONINE
AVAL264FME: N-FORMYLMETHIONINE
AARG322-GLY324FME: N-FORMYLMETHIONINE
ATRP326FME: N-FORMYLMETHIONINE
AHIS333FME: N-FORMYLMETHIONINE
AGLN335FME: N-FORMYLMETHIONINE
BGLY22-GLY23FME: N-FORMYLMETHIONINE
BGLU26FME: N-FORMYLMETHIONINE
CARG2-THR3FME: N-FORMYLMETHIONINE

ND7_6om4_D_101235'-O-[(S)-amino(hydroxy)phosphoryl]adenosine binding site
ChainResidueligand
BGLY122-ILE126ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BASP146-ASP148ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BARG157-GLN158ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BLYS170ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BLEU192-ILE194ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BSER212-PRO216ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BLEU219ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
BTYR239ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine
DALA6-ASP7ND7: 5'-O-[(S)-amino(hydroxy)phosphoryl]adenosine

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Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
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Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
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Catalytic Information from CSA

site_idNumber of ResiduesDetails