6HYJ
PSPH Human phosphoserine phosphatase
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001701 | biological_process | in utero embryonic development |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006563 | biological_process | L-serine metabolic process |
| A | 0006564 | biological_process | L-serine biosynthetic process |
| A | 0009612 | biological_process | response to mechanical stimulus |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031667 | biological_process | response to nutrient levels |
| A | 0033574 | biological_process | response to testosterone |
| A | 0036424 | molecular_function | L-phosphoserine phosphatase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0001701 | biological_process | in utero embryonic development |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006563 | biological_process | L-serine metabolic process |
| B | 0006564 | biological_process | L-serine biosynthetic process |
| B | 0009612 | biological_process | response to mechanical stimulus |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0031667 | biological_process | response to nutrient levels |
| B | 0033574 | biological_process | response to testosterone |
| B | 0036424 | molecular_function | L-phosphoserine phosphatase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 14 |
| 詳細 | binding site for residue SEP A 301 |
| 鎖名 | 残基 |
| A | ASP20 |
| A | HOH408 |
| A | HOH413 |
| A | HOH416 |
| A | HOH422 |
| A | HOH439 |
| A | MET52 |
| A | GLY53 |
| A | SER109 |
| A | GLY110 |
| A | LYS158 |
| A | THR182 |
| A | HOH401 |
| A | HOH403 |
| site_id | AC2 |
| 残基数 | 6 |
| 詳細 | binding site for residue CA A 302 |
| 鎖名 | 残基 |
| A | ASP20 |
| A | ASP22 |
| A | ASP179 |
| A | HOH416 |
| A | HOH422 |
| A | HOH424 |
| site_id | AC3 |
| 残基数 | 4 |
| 詳細 | binding site for residue SEP B 301 |
| 鎖名 | 残基 |
| B | PHE131 |
| B | PRO151 |
| B | LYS168 |
| B | HOH401 |
| site_id | AC4 |
| 残基数 | 6 |
| 詳細 | binding site for residue CA B 302 |
| 鎖名 | 残基 |
| B | ASP20 |
| B | ASP22 |
| B | ASP179 |
| B | HOH420 |
| B | HOH459 |
| B | HOH467 |
| site_id | AC5 |
| 残基数 | 5 |
| 詳細 | binding site for residue SER B 303 |
| 鎖名 | 残基 |
| A | GLN203 |
| A | LYS206 |
| A | ASP207 |
| B | GLU29 |
| B | ARG202 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Nucleophile => ECO:0000305|PubMed:31205021, ECO:0007744|PDB:6HYJ, ECO:0007744|PDB:6HYY, ECO:0007744|PDB:6Q6J |
| 鎖名 | 残基 | 詳細 |
| A | ASP20 | |
| B | ASP20 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | ACT_SITE: Proton donor => ECO:0000305|PubMed:31205021, ECO:0007744|PDB:6HYJ, ECO:0007744|PDB:6HYY, ECO:0007744|PDB:6Q6J |
| 鎖名 | 残基 | 詳細 |
| A | ASP22 | |
| B | ASP22 |
| site_id | SWS_FT_FI3 |
| 残基数 | 6 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:31205021, ECO:0007744|PDB:6HYY |
| 鎖名 | 残基 | 詳細 |
| A | ASP20 | |
| A | ASP22 | |
| A | ASP179 | |
| B | ASP20 | |
| B | ASP22 | |
| B | ASP179 |
| site_id | SWS_FT_FI4 |
| 残基数 | 10 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:31205021, ECO:0007744|PDB:6HYJ, ECO:0007744|PDB:6HYY, ECO:0007744|PDB:6Q6J |
| 鎖名 | 残基 | 詳細 |
| A | MET52 | |
| B | THR182 | |
| A | GLY53 | |
| A | SER109 | |
| A | LYS158 | |
| A | THR182 | |
| B | MET52 | |
| B | GLY53 | |
| B | SER109 | |
| B | LYS158 |
| site_id | SWS_FT_FI5 |
| 残基数 | 2 |
| 詳細 | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:19413330 |
| 鎖名 | 残基 | 詳細 |
| A | MET1 | |
| B | MET1 |
