6G9S

Structural basis for the inhibition of E. coli PBP2

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0004180	molecular_function	carboxypeptidase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

PDBデータベースに由来する情報

site_id	AC1
残基数	12
詳細	binding site for residue ET5 A 701

鎖名	残基
A	ALA329
A	THR547
A	HOH818
A	HOH831
A	SER330
A	LYS333
A	TRP370
A	SER387
A	ASP389
A	ILE453
A	SER545
A	GLY546

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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	1
詳細	ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000269|PubMed:3148617

鎖名	残基	詳細
A	SER330

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