6BPY
Aspergillus fumigatus Thioredoxin Reductase
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0045454 | biological_process | cell redox homeostasis |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 35 |
| 詳細 | binding site for residue FAD A 401 |
| 鎖名 | 残基 |
| A | ILE9 |
| A | ALA37 |
| A | THR40 |
| A | ALA41 |
| A | GLY44 |
| A | GLN45 |
| A | LEU46 |
| A | THR49 |
| A | ILE52 |
| A | ASN54 |
| A | GLU85 |
| A | GLY10 |
| A | THR86 |
| A | ILE87 |
| A | ALA121 |
| A | THR122 |
| A | GLY123 |
| A | TRP138 |
| A | GLN139 |
| A | CYS148 |
| A | ASP149 |
| A | LEU262 |
| A | SER11 |
| A | GLY293 |
| A | ASP294 |
| A | ARG301 |
| A | GLN302 |
| A | ALA303 |
| A | SER306 |
| A | GLY12 |
| A | PRO13 |
| A | ALA14 |
| A | TYR32 |
| A | GLU33 |
| A | GLY34 |
| site_id | AC2 |
| 残基数 | 8 |
| 詳細 | binding site for residue MLI A 402 |
| 鎖名 | 残基 |
| A | THR50 |
| A | GLN139 |
| A | GLY141 |
| A | ILE142 |
| A | ASP149 |
| A | VAL152 |
| A | ILE154 |
| A | PHE155 |
| site_id | AC3 |
| 残基数 | 3 |
| 詳細 | binding site for residue MLI A 403 |
| 鎖名 | 残基 |
| A | VAL147 |
| A | GLU171 |
| B | LEU315 |
| site_id | AC4 |
| 残基数 | 5 |
| 詳細 | binding site for residue MLI A 404 |
| 鎖名 | 残基 |
| A | LEU315 |
| A | GLU318 |
| B | VAL147 |
| B | GLU171 |
| B | FMT406 |
| site_id | AC5 |
| 残基数 | 2 |
| 詳細 | binding site for residue FMT A 405 |
| 鎖名 | 残基 |
| A | GLY133 |
| A | THR136 |
| site_id | AC6 |
| 残基数 | 2 |
| 詳細 | binding site for residue FMT A 406 |
| 鎖名 | 残基 |
| A | ARG299 |
| B | LYS319 |
| site_id | AC7 |
| 残基数 | 10 |
| 詳細 | binding site for residue NAP A 407 |
| 鎖名 | 残基 |
| A | LEU129 |
| A | ILE163 |
| A | GLY165 |
| A | GLY166 |
| A | ASP167 |
| A | SER168 |
| A | ARG188 |
| A | ARG189 |
| A | ARG193 |
| A | VAL254 |
| site_id | AC8 |
| 残基数 | 2 |
| 詳細 | binding site for residue ACT A 408 |
| 鎖名 | 残基 |
| A | SER181 |
| A | SER182 |
| site_id | AC9 |
| 残基数 | 28 |
| 詳細 | binding site for residue FAD B 401 |
| 鎖名 | 残基 |
| B | ILE9 |
| B | GLY10 |
| B | SER11 |
| B | GLY12 |
| B | PRO13 |
| B | ALA14 |
| B | TYR32 |
| B | GLU33 |
| B | GLY34 |
| B | GLY44 |
| B | GLN45 |
| B | LEU46 |
| B | THR49 |
| B | ILE52 |
| B | ASN54 |
| B | ILE87 |
| B | THR122 |
| B | GLY123 |
| B | TRP138 |
| B | GLN139 |
| B | CYS148 |
| B | LEU262 |
| B | GLY293 |
| B | ASP294 |
| B | ARG301 |
| B | GLN302 |
| B | ALA303 |
| B | SER306 |
| site_id | AD1 |
| 残基数 | 1 |
| 詳細 | binding site for residue MLI B 402 |
| 鎖名 | 残基 |
| B | HOH503 |
| site_id | AD2 |
| 残基数 | 6 |
| 詳細 | binding site for residue MLI B 403 |
| 鎖名 | 残基 |
| B | GLY141 |
| B | ASP149 |
| B | VAL152 |
| B | THR50 |
| B | GLN139 |
| B | ASN140 |
| site_id | AD3 |
| 残基数 | 2 |
| 詳細 | binding site for residue FMT B 404 |
| 鎖名 | 残基 |
| B | GLY133 |
| B | THR136 |
| site_id | AD4 |
| 残基数 | 2 |
| 詳細 | binding site for residue FMT B 405 |
| 鎖名 | 残基 |
| B | SER181 |
| B | SER182 |
| site_id | AD5 |
| 残基数 | 2 |
| 詳細 | binding site for residue FMT B 406 |
| 鎖名 | 残基 |
| A | MLI404 |
| B | ARG299 |
| site_id | AD6 |
| 残基数 | 4 |
| 詳細 | binding site for residue FMT B 407 |
| 鎖名 | 残基 |
| A | ARG24 |
| A | PHE78 |
| B | GLU53 |
| B | ALA151 |
| site_id | AD7 |
| 残基数 | 4 |
| 詳細 | binding site for residue FMT B 408 |
| 鎖名 | 残基 |
| A | GLU53 |
| A | ALA151 |
| B | ARG24 |
| B | PHE78 |
| site_id | AD8 |
| 残基数 | 7 |
| 詳細 | binding site for residue NAP B 409 |
| 鎖名 | 残基 |
| B | LEU129 |
| B | GLY165 |
| B | GLY166 |
| B | SER168 |
| B | ARG188 |
| B | ARG193 |
| B | VAL254 |
| site_id | AD9 |
| 残基数 | 7 |
| 詳細 | binding site for residue MLT B 410 |
| 鎖名 | 残基 |
| A | THR305 |
| A | GLY308 |
| A | SER309 |
| B | THR305 |
| B | GLY308 |
| B | SER309 |
| B | ILE312 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00573 |
| 残基数 | 23 |
| 詳細 | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGavpiFrnkpLyVIGGGD |
| 鎖名 | 残基 | 詳細 |
| A | CYS145-ASP167 |
