5ZO6

Crystal structure of C166, a backbone circularized G-CSF

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
X	0005102	molecular_function	signaling receptor binding
X	0005125	molecular_function	cytokine activity
X	0005130	molecular_function	granulocyte colony-stimulating factor receptor binding
X	0005576	cellular_component	extracellular region
X	0005615	cellular_component	extracellular space
X	0006955	biological_process	immune response
X	0008083	molecular_function	growth factor activity
X	0008284	biological_process	positive regulation of cell population proliferation
X	0019221	biological_process	cytokine-mediated signaling pathway
X	0019899	molecular_function	enzyme binding
X	0030838	biological_process	positive regulation of actin filament polymerization
X	0030851	biological_process	granulocyte differentiation
X	0038158	biological_process	granulocyte colony-stimulating factor signaling pathway
X	0043202	cellular_component	lysosomal lumen
X	0045471	biological_process	response to ethanol
X	0045639	biological_process	positive regulation of myeloid cell differentiation
X	0045944	biological_process	positive regulation of transcription by RNA polymerase II
X	0050731	biological_process	positive regulation of peptidyl-tyrosine phosphorylation
X	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
X	0071222	biological_process	cellular response to lipopolysaccharide
X	0071345	biological_process	cellular response to cytokine stimulus
X	0071682	cellular_component	endocytic vesicle lumen
X	0110053	biological_process	regulation of actin filament organization

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00254
残基数	26
詳細	INTERLEUKIN_6 Interleukin-6 / G-CSF / MGF signature. CpsqalqlagClsqlhsGLflYqglL

鎖名	残基	詳細
X	CYS58-LEU83

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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id	SWS_FT_FI1
残基数	1
詳細	CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000250

鎖名	残基	詳細
X	ALA130

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