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5FCK

COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND 5

Functional Information from GO Data
ChainGOidnamespacecontents
A0002376biological_processimmune system process
A0004252molecular_functionserine-type endopeptidase activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0006956biological_processcomplement activation
A0006957biological_processcomplement activation, alternative pathway
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0009617biological_processresponse to bacterium
A0016787molecular_functionhydrolase activity
A0031093cellular_componentplatelet alpha granule lumen
A0034774cellular_componentsecretory granule lumen
A0045087biological_processinnate immune response
A0070062cellular_componentextracellular exosome
A1904813cellular_componentficolin-1-rich granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues21
Detailsbinding site for residue 5WC A 301
ChainResidue
AHIS40
ACYS191
ALYS192
AGLY193
ASER195
AVAL213
ATHR214
ASER215
AGLY216
AARG218
ACYS220
ALEU41
AHOH406
AHOH466
ACYS42
AHIS57
ACYS58
ATRP141
AILE143
AARG151
ASER190

site_idAC2
Number of Residues10
Detailsbinding site for residue SO4 A 302
ChainResidue
AGLU21
AALA22
AARG179
AALA232
ASER233
ATYR234
AALA235
AALA236
AHOH416
AHOH417

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC
ChainResidueDetails
ALEU53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV
ChainResidueDetails
AASP189-VAL200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS57
AASP102
ASER195

218853

건을2024-04-24부터공개중

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