5CUQ

Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
B	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
B	0004483	molecular_function	mRNA (nucleoside-2'-O-)-methyltransferase activity
B	0008168	molecular_function	methyltransferase activity
B	0032259	biological_process	methylation

PDBデータベースに由来する情報

site_id	AC1
残基数	9
詳細	binding site for residue NSC A 301

鎖名	残基
A	GLY81
A	GLY109
A	HIS110
A	GLU111
A	LYS130
A	ASP131
A	VAL132
A	PHE133
A	ILE147

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site_id	AC2
残基数	13
詳細	binding site for residue NSC B 301

鎖名	残基
B	GLY81
B	THR104
B	LYS105
B	GLY109
B	HIS110
B	GLU111
B	ASP131
B	VAL132
B	PHE133
B	HOH441
B	HOH497
B	HOH578
B	HOH598

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