4Z2L

Serratia marcescens Chitinase B complexed with macrolide inhibitor 33

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding
A	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue M6F A 501

Chain	Residue
A	TYR10
A	TYR292
A	ARG294
A	ASP316
A	HOH709
A	HOH749
A	PHE12
A	PHE51
A	TYR98
A	ASP142
A	GLU144
A	MET212
A	TYR214
A	ASP215

---

site_id	AC2
Number of Residues	5
Details	binding site for residue GOL A 502

Chain	Residue
A	ARG244
A	PHE259
A	PRO260
A	SER261
A	HOH808

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 503

Chain	Residue
A	PRO260
A	PHE263
A	SER264
A	ARG439
A	TYR440
A	THR441
A	HOH630
A	HOH655

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 504

Chain	Residue
A	ARG162
A	ALA204
A	ASP207
A	LYS284

---

site_id	AC5
Number of Residues	4
Details	binding site for residue GOL A 505

Chain	Residue
A	PHE190
A	TYR240
A	TRP479
A	GLY480

---

site_id	AC6
Number of Residues	1
Details	binding site for residue CL A 506

Chain	Residue
A	ARG89

---

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGVDIDwE

Chain	Residue	Details
A	PHE136-GLU144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	GLU144

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	ASP68
A	GLY95
A	TYR145
A	MET212
A	TRP403

---