4PVS
Crystal structure of fully-cleaved human l-asparaginase protein in complex with l-aspartate
「4GDW」から置き換えられましたGO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0001917 | cellular_component | photoreceptor inner segment |
| A | 0003948 | molecular_function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| A | 0004067 | molecular_function | asparaginase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008798 | molecular_function | beta-aspartyl-peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0033345 | biological_process | L-asparagine catabolic process via L-aspartate |
| B | 0001917 | cellular_component | photoreceptor inner segment |
| B | 0003948 | molecular_function | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity |
| B | 0004067 | molecular_function | asparaginase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008798 | molecular_function | beta-aspartyl-peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0033345 | biological_process | L-asparagine catabolic process via L-aspartate |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE NA A 401 |
| 鎖名 | 残基 |
| A | LEU55 |
| A | GLU56 |
| A | ASP58 |
| A | PHE61 |
| A | ALA63 |
| A | CYS65 |
| site_id | AC2 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE ASP A 402 |
| 鎖名 | 残基 |
| A | ASP199 |
| A | THR219 |
| A | GLY220 |
| A | GLY222 |
| A | HOH503 |
| A | HOH569 |
| A | THR168 |
| A | GLY188 |
| A | ARG196 |
| site_id | AC3 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE NA B 401 |
| 鎖名 | 残基 |
| B | LEU55 |
| B | GLU56 |
| B | ASP58 |
| B | PHE61 |
| B | ALA63 |
| B | CYS65 |
| site_id | AC4 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE ASP B 402 |
| 鎖名 | 残基 |
| B | THR168 |
| B | GLY188 |
| B | ARG196 |
| B | ASP199 |
| B | THR219 |
| B | GLY220 |
| B | GLY222 |
| B | HOH504 |
| B | HOH548 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19839645","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22861376","evidenceCode":"ECO:0000269"}]} |
| 鎖名 | 残基 | 詳細 |
| site_id | SWS_FT_FI2 |
| 残基数 | 12 |
| 詳細 | Binding site: {} |
| 鎖名 | 残基 | 詳細 |
| site_id | SWS_FT_FI3 |
| 残基数 | 2 |
| 詳細 | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]} |
| 鎖名 | 残基 | 詳細 |
