Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE HEM A 401 |
Chain | Residue |
A | MET74 |
A | THR244 |
A | SER283 |
A | LEU286 |
A | ARG288 |
A | GLY338 |
A | PHE339 |
A | GLY340 |
A | ILE343 |
A | HIS344 |
A | CYS346 |
A | SER75 |
A | LEU347 |
A | GLY348 |
A | HOH501 |
A | HOH514 |
A | HIS82 |
A | ARG86 |
A | ILE137 |
A | LEU233 |
A | THR236 |
A | GLY237 |
A | THR240 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGrGIHFCLG |
Chain | Residue | Details |
A | PHE339-GLY348 | |