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4A5W

Crystal structure of C5b6

Functional Information from GO Data
ChainGOidnamespacecontents
A0002376biological_processimmune system process
A0004866molecular_functionendopeptidase inhibitor activity
A0005102molecular_functionsignaling receptor binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005579cellular_componentmembrane attack complex
A0005615cellular_componentextracellular space
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006957biological_processcomplement activation, alternative pathway
A0006958biological_processcomplement activation, classical pathway
A0007166biological_processcell surface receptor signaling pathway
A0007186biological_processG protein-coupled receptor signaling pathway
A0008009molecular_functionchemokine activity
A0010575biological_processpositive regulation of vascular endothelial growth factor production
A0010760biological_processnegative regulation of macrophage chemotaxis
A0031640biological_processkilling of cells of another organism
A0032722biological_processpositive regulation of chemokine production
A0045087biological_processinnate immune response
A0050896biological_processresponse to stimulus
A0060326biological_processcell chemotaxis
A0070062cellular_componentextracellular exosome
B0001701biological_processin utero embryonic development
B0002376biological_processimmune system process
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005579cellular_componentmembrane attack complex
B0005615cellular_componentextracellular space
B0005886cellular_componentplasma membrane
B0006955biological_processimmune response
B0006956biological_processcomplement activation
B0006958biological_processcomplement activation, classical pathway
B0031640biological_processkilling of cells of another organism
B0045087biological_processinnate immune response
B0050778biological_processpositive regulation of immune response
B0070062cellular_componentextracellular exosome
Functional Information from PROSITE/UniProt
site_idPS00022
Number of Residues12
DetailsEGF_1 EGF-like domain signature 1. CvCqsGtyGEnC
ChainResidueDetails
BCYS541-CYS552

site_idPS00279
Number of Residues12
DetailsMACPF_1 Membrane attack complex/perforin (MACPF) domain signature. YsrifddFGTHY
ChainResidueDetails
BTYR354-TYR365

site_idPS01209
Number of Residues23
DetailsLDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIarkle.CNgenDCgdn.SDErd...C
ChainResidueDetails
BCYS151-CYS173

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: C-linked (Man) tryptophan => ECO:0000269|PubMed:10551839
ChainResidueDetails
BTRP29

site_idSWS_FT_FI2
Number of Residues5
DetailsCARBOHYD: C-linked (Man) tryptophan; partial => ECO:0000269|PubMed:10551839
ChainResidueDetails
BTRP32
BTRP90
BTRP568
BTRP571
BTRP574

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: O-linked (Fuc...) threonine => ECO:0000305|PubMed:22267737
ChainResidueDetails
BTHR38
BTHR392

site_idSWS_FT_FI4
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:22267737
ChainResidueDetails
BASN324

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952
ChainResidueDetails
BASN855

218853

건을2024-04-24부터공개중

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