Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ZTQ

Hexagonal crystal form P61 of the Aquifex aeolicus nucleoside diphosphate kinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006163	biological_process	purine nucleotide metabolic process
A	0006183	biological_process	GTP biosynthetic process
A	0006220	biological_process	pyrimidine nucleotide metabolic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006163	biological_process	purine nucleotide metabolic process
B	0006183	biological_process	GTP biosynthetic process
B	0006220	biological_process	pyrimidine nucleotide metabolic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006163	biological_process	purine nucleotide metabolic process
C	0006183	biological_process	GTP biosynthetic process
C	0006220	biological_process	pyrimidine nucleotide metabolic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006163	biological_process	purine nucleotide metabolic process
D	0006183	biological_process	GTP biosynthetic process
D	0006220	biological_process	pyrimidine nucleotide metabolic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006163	biological_process	purine nucleotide metabolic process
E	0006183	biological_process	GTP biosynthetic process
E	0006220	biological_process	pyrimidine nucleotide metabolic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0016740	molecular_function	transferase activity
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006163	biological_process	purine nucleotide metabolic process
F	0006183	biological_process	GTP biosynthetic process
F	0006220	biological_process	pyrimidine nucleotide metabolic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009117	biological_process	nucleotide metabolic process
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0016740	molecular_function	transferase activity
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006163	biological_process	purine nucleotide metabolic process
G	0006183	biological_process	GTP biosynthetic process
G	0006220	biological_process	pyrimidine nucleotide metabolic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009117	biological_process	nucleotide metabolic process
G	0016301	molecular_function	kinase activity
G	0016310	biological_process	phosphorylation
G	0016740	molecular_function	transferase activity
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006163	biological_process	purine nucleotide metabolic process
H	0006183	biological_process	GTP biosynthetic process
H	0006220	biological_process	pyrimidine nucleotide metabolic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009117	biological_process	nucleotide metabolic process
H	0016301	molecular_function	kinase activity
H	0016310	biological_process	phosphorylation
H	0016740	molecular_function	transferase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NaiHASDSP

Chain	Residue	Details
A	ASN117-PRO125

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255\|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	HIS120
B	HIS120
C	HIS120
D	HIS120
E	HIS120
F	HIS120
G	HIS120
H	HIS120

site_id	SWS_FT_FI2
Number of Residues	48
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00451

Chain	Residue	Details
A	LYS11
B	THR93
B	ARG107
B	ASN117
C	LYS11
C	PHE59
C	ARG87
C	THR93
C	ARG107
C	ASN117
D	LYS11
A	PHE59
D	PHE59
D	ARG87
D	THR93
D	ARG107
D	ASN117
E	LYS11
E	PHE59
E	ARG87
E	THR93
E	ARG107
A	ARG87
E	ASN117
F	LYS11
F	PHE59
F	ARG87
F	THR93
F	ARG107
F	ASN117
G	LYS11
G	PHE59
G	ARG87
A	THR93
G	THR93
G	ARG107
G	ASN117
H	LYS11
H	PHE59
H	ARG87
H	THR93
H	ARG107
H	ASN117
A	ARG107
A	ASN117
B	LYS11
B	PHE59
B	ARG87

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)