3SS4

Crystal structure of mouse Glutaminase C, phosphate-bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004359	molecular_function	glutaminase activity
A	0006541	biological_process	glutamine metabolic process
B	0004359	molecular_function	glutaminase activity
B	0006541	biological_process	glutamine metabolic process
C	0004359	molecular_function	glutaminase activity
C	0006541	biological_process	glutamine metabolic process
D	0004359	molecular_function	glutaminase activity
D	0006541	biological_process	glutamine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 A 1

Chain	Residue
A	HOH29
A	SER291
A	ASN340
A	TYR471
A	HOH611

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 B 2

Chain	Residue
B	HOH614
B	HOH94
B	SER291
B	ASN340
B	TYR471

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 3

Chain	Residue
C	SER291
C	ASN340
C	TYR471
C	HOH613

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 D 4

Chain	Residue
D	SER291
D	ASN340
D	ARG392
D	HOH629

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	BINDING: BINDING => ECO:0000269|PubMed:22228304, ECO:0007744|PDB:3SS5

Chain	Residue	Details
A	VAL285
B	ASN380
B	ARG387
B	VAL413
B	MET465
B	LEU483
C	VAL285
C	PRO334
C	ASN380
C	ARG387
C	VAL413
A	PRO334
C	MET465
C	LEU483
D	VAL285
D	PRO334
D	ASN380
D	ARG387
D	VAL413
D	MET465
D	LEU483
A	ASN380
A	ARG387
A	VAL413
A	MET465
A	LEU483
B	VAL285
B	PRO334

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site_id	SWS_FT_FI2
Number of Residues	8
Details	MOD_RES: N6-succinyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	VAL129
A	LYS163
B	VAL129
B	LYS163
C	VAL129
C	LYS163
D	VAL129
D	LYS163

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site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O94925

Chain	Residue	Details
A	VAL310
B	VAL310
C	VAL310
D	VAL310

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