3SKE
I. Novel HCV NS5B Polymerase Inhibitors: Discovery of Indole 2- Carboxylic Acids with C3-Heterocycles
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE PO4 A 577 |
| 鎖名 | 残基 |
| A | PRO265 |
| A | ARG505 |
| A | VAL530 |
| A | ARG531 |
| A | THR532 |
| A | HOH662 |
| A | HOH854 |
| A | HOH951 |
| A | HOH970 |
| site_id | AC2 |
| 残基数 | 18 |
| 詳細 | BINDING SITE FOR RESIDUE 054 A 578 |
| 鎖名 | 残基 |
| A | PRO197 |
| A | ASN316 |
| A | CYS366 |
| A | SER368 |
| A | LEU384 |
| A | SER407 |
| A | GLY410 |
| A | ASN411 |
| A | MET414 |
| A | TYR415 |
| A | GLN446 |
| A | ILE447 |
| A | TYR448 |
| A | HOH624 |
| A | HOH700 |
| A | HOH728 |
| A | HOH915 |
| A | HOH944 |
| site_id | AC3 |
| 残基数 | 17 |
| 詳細 | BINDING SITE FOR RESIDUE 054 B 577 |
| 鎖名 | 残基 |
| B | PRO197 |
| B | ASN316 |
| B | CYS366 |
| B | SER368 |
| B | LEU384 |
| B | SER407 |
| B | GLY410 |
| B | ASN411 |
| B | MET414 |
| B | TYR415 |
| B | GLN446 |
| B | ILE447 |
| B | TYR448 |
| B | HOH643 |
| B | HOH727 |
| B | HOH750 |
| B | HOH848 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 6 |
| 詳細 | BINDING: BINDING => ECO:0000250|UniProtKB:P26663 |
| 鎖名 | 残基 | 詳細 |
| A | ASP220 | |
| A | ASP318 | |
| A | ASP319 | |
| B | ASP220 | |
| B | ASP318 | |
| B | ASP319 |
| site_id | SWS_FT_FI2 |
| 残基数 | 4 |
| 詳細 | MOD_RES: Phosphoserine; by host => ECO:0000250|UniProtKB:P26662 |
| 鎖名 | 残基 | 詳細 |
| A | SER29 | |
| A | SER42 | |
| B | SER29 | |
| B | SER42 |
