Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005048 | molecular_function | signal sequence binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006605 | biological_process | protein targeting |
| A | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| A | 0008320 | molecular_function | protein transmembrane transporter activity |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0031204 | biological_process | post-translational protein targeting to membrane, translocation |
| A | 0043022 | molecular_function | ribosome binding |
| A | 0065002 | biological_process | intracellular protein transmembrane transport |
| B | 0006605 | biological_process | protein targeting |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0008320 | molecular_function | protein transmembrane transporter activity |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00318 |
| Number of Residues | 8 |
| Details | HMG_COA_REDUCTASE_2 Hydroxymethylglutaryl-coenzyme A reductases signature 2. IGaLGGGT |
| Chain | Residue | Details |
| A | ILE393-THR400 | |
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. TLItLGIgPIVtAGIIMQLL |
| Chain | Residue | Details |
| A | THR69-LEU88 | |
| site_id | PS00756 |
| Number of Residues | 18 |
| Details | SECY_2 Protein secY signature 2. YLdEiVSky.GIGSGiGLF |
| Chain | Residue | Details |
| A | TYR156-PHE173 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical |
| Chain | Residue | Details |
| C | GLU31-TYR49 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 70 |
| Details | TOPO_DOM: Extracellular |
| Chain | Residue | Details |
| A | THR47-ILE55 | |
| A | GLY130-ALA140 | |
| A | TYR192-TYR209 | |
| A | ARG278-ASP312 | |
| A | GLY398 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | TRANSMEM: Discontinuously helical; Name=Helix 2 |
| Chain | Residue | Details |
| A | PHE56-LEU88 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | INTRAMEM: Helical; Name=Helix 2A |
| Chain | Residue | Details |
| A | PHE56-THR63 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | INTRAMEM: |
| Chain | Residue | Details |
| A | ALA64-THR69 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 18 |
| Details | INTRAMEM: Helical; Name=Helix 2B |
| Chain | Residue | Details |
| A | LEU70-LEU88 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 104 |
| Details | TOPO_DOM: Cytoplasmic |
| Chain | Residue | Details |
| A | VAL89-CYS110 | |
| A | SER162-SER168 | |
| A | CYS228-SER255 | |
| A | ILE332-PHE382 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=Helix 3 |
| Chain | Residue | Details |
| A | GLN111-ALA129 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=Helix 4 |
| Chain | Residue | Details |
| A | PHE141-VAL161 | |
| site_id | SWS_FT_FI10 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=Helix 5 |
| Chain | Residue | Details |
| A | GLY169-GLY191 | |
| site_id | SWS_FT_FI11 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=Helix 6 |
| Chain | Residue | Details |
| A | ILE210-GLU227 | |
| site_id | SWS_FT_FI12 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=Helix 7 |
| Chain | Residue | Details |
| A | ASN256-TYR277 | |
| site_id | SWS_FT_FI13 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=Helix 8 |
| Chain | Residue | Details |
| A | PRO313-GLY331 | |
| site_id | SWS_FT_FI14 |
| Number of Residues | 14 |
| Details | TRANSMEM: Helical; Name=Helix 9 |
| Chain | Residue | Details |
| A | VAL383-GLY397 | |
| site_id | SWS_FT_FI15 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=Helix 10 |
| Chain | Residue | Details |
| A | GLY399-MET412 | |
| site_id | SWS_FT_FI16 |
| Number of Residues | 6 |
| Details | SITE: Pore ring |
| Chain | Residue | Details |
| A | ILE75 | |
| A | VAL79 | |
| A | ILE174 | |
| A | SER179 | |
| A | ILE260 | |
| A | VAL406 | |
