2V0G

LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site.

GO（遺伝子オントロジー）由来の情報

鎖名	GO（遺伝子オントロジー）id	名前空間	内容
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA editing activity
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004823	molecular_function	leucine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006429	biological_process	leucyl-tRNA aminoacylation
A	0046872	molecular_function	metal ion binding
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
D	0000166	molecular_function	nucleotide binding
D	0002161	molecular_function	aminoacyl-tRNA editing activity
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004823	molecular_function	leucine-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006412	biological_process	translation
D	0006418	biological_process	tRNA aminoacylation for protein translation
D	0006429	biological_process	leucyl-tRNA aminoacylation
D	0046872	molecular_function	metal ion binding
D	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

PDBデータベースに由来する情報

site_id	AC1
残基数	4
詳細	BINDING SITE FOR RESIDUE ZN A1877

鎖名	残基
A	CYS439
A	CYS442
A	CYS484
A	CYS487

---

site_id	AC2
残基数	4
詳細	BINDING SITE FOR RESIDUE ZN A1878

鎖名	残基
A	CYS159
A	CYS162
A	CYS176
A	HIS179

---

site_id	AC3
残基数	3
詳細	BINDING SITE FOR RESIDUE HG A1879

鎖名	残基
A	CYS128
A	GLU129
A	TYR102

---

site_id	AC4
残基数	1
詳細	BINDING SITE FOR RESIDUE SO4 A1880

鎖名	残基
A	ARG762

---

site_id	AC5
残基数	3
詳細	BINDING SITE FOR RESIDUE SO4 A1881

鎖名	残基
A	GLY707
A	ARG769
A	TRP795

---

site_id	AC6
残基数	4
詳細	BINDING SITE FOR RESIDUE SO4 A1882

鎖名	残基
A	HIS49
A	HIS52
A	SER639
A	LYS640

---

site_id	AC7
残基数	1
詳細	BINDING SITE FOR RESIDUE SO4 A1883

鎖名	残基
A	ARG759

---

site_id	AC8
残基数	1
詳細	BINDING SITE FOR RESIDUE SO4 A1884

鎖名	残基
A	LYS288

---

site_id	AC9
残基数	4
詳細	BINDING SITE FOR RESIDUE SO4 A1885

鎖名	残基
A	ARG32
A	GLN69
A	GLY70
A	TYR71

---

site_id	BC1
残基数	5
詳細	BINDING SITE FOR RESIDUE SO4 A1886

鎖名	残基
A	GLU264
A	LEU329
A	PHE330
A	GLY331
A	ARG420

---

site_id	BC2
残基数	6
詳細	BINDING SITE FOR RESIDUE SO4 D1877

鎖名	残基
D	SER706
D	GLY707
D	VAL708
D	ARG769
D	ARG773
D	TRP795

---

site_id	BC3
残基数	1
詳細	BINDING SITE FOR RESIDUE SO4 D1878

鎖名	残基
D	ARG759

---

site_id	BC4
残基数	4
詳細	BINDING SITE FOR RESIDUE SO4 D1879

鎖名	残基
D	GLU264
D	PHE330
D	GLY331
D	ARG420

---

site_id	BC5
残基数	3
詳細	BINDING SITE FOR RESIDUE ZN D1880

鎖名	残基
D	CYS439
D	CYS484
D	CYS487

---

site_id	BC6
残基数	4
詳細	BINDING SITE FOR RESIDUE ZN D1881

鎖名	残基
D	CYS159
D	CYS162
D	CYS176
D	HIS179

---

site_id	BC7
残基数	2
詳細	BINDING SITE FOR RESIDUE HG D1882

鎖名	残基
D	CYS128
D	GLU129

---

site_id	BC8
残基数	8
詳細	BINDING SITE FOR RESIDUE LEU A1887

鎖名	残基
A	MET40
A	PHE41
A	TYR43
A	ASP80
A	SER504
A	TYR535
A	HIS541
A	HIS545

---

site_id	BC9
残基数	4
詳細	BINDING SITE FOR RESIDUE LEU D1883

鎖名	残基
D	PHE41
D	PRO42
D	TYR43
D	HIS541

---

UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id	PS00178
残基数	12
詳細	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGdLHMGHL

鎖名	残基	詳細
A	PRO42-LEU53

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